Evidence map›Paper›PMID 38296708›Full record

ReviewTrends in genetics : TIG2024

How intrinsically disordered proteins order plant gene silencing.

Baoshuan Shang, Changhao Li, Xiuren Zhang

Open access · greenAbstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Baoshuan ShangNational Key Laboratory of Cotton Bio-breeding and Integrated Utilization (Henan University), State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng 475004, China; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Changhao LiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Xiuren ZhangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA; Department of Biology, Texas A&M University, College Station, TX 77843, USA. Electronic address: xiuren.zhang@tamu.edu.
Texas A&M University · USHenan University · CN

Funding

Roles of SWI/SNF complexes in posttranscriptional processing of RNAR01GM132401 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2019 to 2022
$1.4M
Suppression mechanism of Geminivirus-encoded TrAP proteinR01GM127742 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2019 to 2022
$1.2M
Functions and mechanisms of new components in RNA silencing--Admin SuppR35GM151976 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2024 to 2025
$1.1M
NIGMS NIH HHS R01 GM127742NIGMS NIH HHS R01 GM132401NIGMS NIH HHS R35 GM151976
6 · The paper itself

Abstract

Intrinsically disordered proteins (IDPs) and proteins with intrinsically disordered regions (IDRs) possess low sequence complexity of amino acids and display non-globular tertiary structures. They can act as scaffolds, form regulatory hubs, or trigger biomolecular condensation to control diverse aspects of biology. Emerging evidence has recently implicated critical roles of IDPs and IDR-contained proteins in nuclear transcription and cytoplasmic post-transcriptional processes, among other molecular functions. We here summarize the concepts and organizing principles of IDPs. We then illustrate recent progress in understanding the roles of key IDPs in machineries that regulate transcriptional and post-transcriptional gene silencing (PTGS) in plants, aiming at highlighting new modes of action of IDPs in controlling biological processes.

Indexed as

Intrinsically Disordered ProteinsGene SilencingPlantsProtein ConformationIntrinsically Disordered Proteinsgene silencingintrinsically disordered protein (IDP)intrinsically disordered region (IDR)liquid–liquid phase separationmiRNAsiRNA

Identifiers

PMID38296708
PMCPMC10932933
OpenAlexW4391338697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.