Evidence map›Paper›PMID 38296485›Full record

ArticleInternal medicine (Tokyo, Japan)2024

A 70-year-old Woman with Asymptomatic Ferroportin Disease.

Tetsuya Ishikawa, Yasuaki Tatsumi, Koichi Kato, Yumi Hayashi, Norihiro Imai, Takanori Ito, Yoji Ishizu, Masatoshi Ishigami, Wataru Nihei, Ayako Kato and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Tetsuya IshikawaDepartment of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Japan.
Yasuaki TatsumiDepartment of Medical Biochemistry, Faculty of Pharmaceutical Sciences, Toho University, Japan.
Koichi KatoDepartment of Medicine, Aichi Gakuin University School of Pharmacy, Japan.
Yumi HayashiDepartment of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Japan.
Norihiro ImaiDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Japan.
Takanori ItoDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Japan.
Yoji IshizuDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Japan.
Masatoshi IshigamiDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Japan.
Wataru NiheiDepartment of Medicine, Aichi Gakuin University School of Pharmacy, Japan.
Ayako KatoDepartment of Medicine, Aichi Gakuin University School of Pharmacy, Japan.
Hisao HayashiDepartment of Medicine, Aichi Gakuin University School of Pharmacy, Japan.
Nagoya University · JPAichi Gakuin University · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59-year-old Japanese woman presented with hyperferritinemia. We decided against iron removal treatment because there were no symptoms or signs of iron-induced organ damage. A follow-up study revealed a gradual increase in transferrin saturation. The patient underwent a second examination at 66 years old. A liver biopsy showed substantial iron deposits in hepatocytes and Kupffer cells but no inflammation or fibrosis. Serum hepcidin-25 levels were highly parallel with hyperferritinemia. A genetic analysis revealed a G80S mutation in SLC40A1. These features are compatible with those of ferroportin disease. The patient remained asymptomatic at 70 years old, suggesting that the iron-loading condition may have been benign.

Indexed as

Cation Transport ProteinsAsymptomatic DiseasesFemaleFerroportinHepcidinsHumansHyperferritinemiaIronLiverMiddle AgedMutationCation Transport ProteinsFerroportinHepcidinsIronferritinferroportinhemochromatosishepcidiniron

Identifiers

PMID38296485
PMCPMC11442921
OpenAlexW4391378607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.