Evidence map›Paper›PMID 38295882›Full record

ArticleThe Journal of allergy and clinical immunology2024

Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop.

Supinda Bunyavanich, Patrice M Becker, Matthew C Altman, Jessica Lasky-Su, Carole Ober, Karsten Zengler, Evgeny Berdyshev, Richard Bonneau, Talal Chatila, Nilanjan Chatterjee and 20 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Multiomic approaches for endotype discovery in allergy/immunology.The Journal of allergy and clinical immunology · 2025
    Article
  4. Review
  5. Immunomodulatory metabolites in IgE-mediated food allergy and oral immunotherapy outcomes based on metabolomic profiling.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 17 institutions in 2 countries.

Supinda BunyavanichIcahn School of Medicine at Mount Sinai, New York, NY. Electronic address: supinda@post.harvard.edu.
Patrice M BeckerNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Matthew C AltmanUniversity of Washington, Seattle, Wash.
Jessica Lasky-SuBrigham & Women's Hospital and Harvard Medical School, Boston, Mass.
Carole OberUniversity of Chicago, Chicago, Ill.
Karsten ZenglerUniversity of California, San Diego, Calif.
Evgeny BerdyshevNational Jewish Health, Denver, Colo.
Richard BonneauGenentech, New York, NY.
Talal ChatilaBoston Children's Hospital and Harvard Medical School, Boston, Mass.
Nilanjan ChatterjeeJohns Hopkins University, Baltimore, Md.
Kian Fan ChungImperial College, London, United Kingdom.
Colleen CutcliffePendulum Therapeutics, San Francisco, Calif.
Wendy DavidsonNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Gang DongNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Gang FangIcahn School of Medicine at Mount Sinai, New York, NY.
Patricia FulkersonNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Blanca E HimesUniversity of Pennsylvania, Philadelphia, Pa.
Liming LiangHarvard T. H. Chan School of Public Health, Boston, Mass.
Rasika A MathiasJohns Hopkins University, Baltimore, Md.
Shuji OginoBrigham & Women's Hospital and Harvard Medical School, Boston, Mass; Harvard T. H. Chan School of Public Health, Boston, Mass; Broad Institute of MIT and Harvard, Boston, Mass.
Joseph PetrosinoBaylor College of Medicine, Houston, Tex.
Nathan D PriceThorne HealthTech, New York, NY.
Eric SchadtIcahn School of Medicine at Mount Sinai, New York, NY.
James SchofieldUniversity of Southampton, Southampton, United Kingdom.
Max A SeiboldNational Jewish Health, Denver, Colo; University of Colorado School of Medicine, Aurora, Colo.
Hanno SteenBoston Children's Hospital and Harvard Medical School, Boston, Mass.
Lisa WheatleyNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Hongmei ZhangSchool of Public Health, University of Memphis, Memphis, Tenn.
Alkis TogiasNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Kohei HasegawaMassachusetts General Hospital and Harvard Medical School, Boston, Mass.
National Institutes of Health · USIcahn School of Medicine at Mount Sinai · USBoston Children's Hospital · USHarvard University · USJohns Hopkins University · USNational Jewish Health · USBaylor College of Medicine · USBrigham and Women's Hospital · USBroad Institute · USHamilton Thorne (United States) · USImperial College London · GBUniversity of California San Diego · USUniversity of Chicago · USUniversity of Memphis · USUniversity of Pennsylvania · USUniversity of Southampton · GBUniversity of Washington · US

Funding

Systems Biology of Early Atopy (SUNBEAM) Analysis and Bioinformatics CenterUM1AI173380 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Supinda Bunyavanich · 2023 to 2026
$10.4M
Threshold, Severity, and Immunotherapy of Peanut AllergyU19AI136053 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BUNYAVANICH, SUPINDA · 2018 to 2023
$9.1M
Infant blood epigenome and risks of IgE sensitization, obesity, and asthma: MARC-35/43 cohortsR01AI148338 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI CAMARGO, CARLOS ARTURO, LIANG, LIMING · 2020 to 2023
$2.5M
NIAID NIH HHS R01 AI148338NIAID NIH HHS U19 AI136053NIAID NIH HHS UM1 AI173380
6 · The paper itself

Abstract

Studies of asthma and allergy are generating increasing volumes of omics data for analysis and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) assembled a workshop comprising investigators studying asthma and allergic diseases using omics approaches, omics investigators from outside the field, and NIAID medical and scientific officers to discuss the following areas in asthma and allergy research: genomics, epigenomics, transcriptomics, microbiomics, metabolomics, proteomics, lipidomics, integrative omics, systems biology, and causal inference. Current states of the art, present challenges, novel and emerging strategies, and priorities for progress were presented and discussed for each area. This workshop report summarizes the major points and conclusions from this NIAID workshop. As a group, the investigators underscored the imperatives for rigorous analytic frameworks, integration of different omics data types, cross-disciplinary interaction, strategies for overcoming current limitations, and the overarching goal to improve scientific understanding and care of asthma and allergic diseases.

Indexed as

AsthmaHypersensitivityGenomicsHumansMetabolomicsNational Institute of Allergy and Infectious Diseases (U.S.)ProteomicsUnited Statesallergic diseasesallergyasthmacausal inferenceepigenomicsgenomicsintegrativelipidomicsmetabolomicsmicrobiomeOmicsproteomicssystems biologytranscriptomics

Identifiers

PMID38295882
PMCPMC10999353
OpenAlexW4391325343

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.