Evidence map›Paper›PMID 38295871›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2024

The associations between synaptic density and "A/T/N" biomarkers in Alzheimer's disease: An

Junpeng Li, Qi Huang, Na Qi, Kun He, Songye Li, Lin Huang, Fengfeng Pan, Shuhua Ren, Fengchun Hua, Yiyun Huang and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Impaired glymphatic function is associated with synaptic loss in cognitive impairment.European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Prediction of longitudinal synaptic loss in Alzheimer's disease using tau PET and plasma biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Imaging Synaptic Density in Aging and Alzheimer Disease with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Junpeng LiDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Qi HuangDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Na QiDepartment of Nuclear Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Kun HeDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Songye LiPET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.
Lin HuangDepartment of Gerontology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Fengfeng PanDepartment of Gerontology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Shuhua RenDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Fengchun HuaDepartment of Nuclear Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yiyun HuangPET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.
Yihui GuanDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Qihao GuoDepartment of Gerontology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Jun ZhaoDepartment of Nuclear Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Fang XieDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CNShanghai Sixth People's Hospital · CNShanghai East Hospital · CNYale University · USLonghua Hospital Shanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A newly developed SV2A radiotracer,

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesBiomarkersSynapsesAgedAged, 80 and overCognitive DysfunctionFemaleFluorine RadioisotopesHumansMagnetic Resonance ImagingMaleMembrane GlycoproteinsMiddle AgedNerve Tissue ProteinsPositron-Emission TomographyAmyloid beta-PeptidesBiomarkersFluorine RadioisotopesMembrane GlycoproteinsNerve Tissue ProteinsRadiopharmaceuticalsSV2A protein, humantau Proteinsamyloid-β depositioncognitive performanceglucose metabolismplasma biomarkersSynaptic vesicle glycoprotein 2A

Identifiers

PMID38295871
PMCPMC11179616
OpenAlexW4392788577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.