Evidence map›Paper›PMID 38295647›Full record

ArticleBiochemical and biophysical research communications2024

Suppressor analysis links trans-translation and ribosomal protein uS7 to RluD function in Escherichia coli.

Zachary S Clark, Michael O'Connor

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical and biophysical research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zachary S ClarkDivision of Biology and Biomedical Systems, School of Science and Engineering, 306 Spencer Hall, University of Missouri-Kansas City, 5007 Rockhill Rd., Kansas City, MO, 64110, USA.
Michael O'ConnorDivision of Biology and Biomedical Systems, School of Science and Engineering, 306 Spencer Hall, University of Missouri-Kansas City, 5007 Rockhill Rd., Kansas City, MO, 64110, USA. Electronic address: oconnormi@umkc.edu.
University of Missouri–Kansas City · US

Funding

Pseudouridine Function in Ribosomal RNAR15GM132752 · NIGMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI O'CONNOR, MICHAEL · 2019 to 2019
$361k
NIGMS NIH HHS R15 GM132752
6 · The paper itself

Abstract

The pseudouridine (ψ) synthase, RluD is responsible for three ψ modifications in the helix 69 (H69) of bacterial 23S rRNA. While normally dispensable, rluD becomes critical for rapid cell growth in bacteria that are defective in translation-termination. In slow-growing rluD

Indexed as

Escherichia coliEscherichia coli ProteinsCodon, TerminatorHydro-LyasesProtein BiosynthesisRibosomal ProteinsCodon, TerminatorEscherichia coli ProteinsHydro-LyasesRibosomal ProteinsRluD protein, E coli23S rRNAPseudouridineRelease factorsRibosomal protein uS7SuppressionTerminationTrans-translation

Identifiers

PMID38295647
PMCPMC10878134
OpenAlexW4391248451

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.