ArticleScience advances2024
Distinct manifold encoding of navigational information in the subiculum and hippocampus.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Encoding Patterned Spatial Behavior in the Subiculum.Hippocampus · 2026Review
- Top-down regulation of ingestive behavior fragmentation.bioRxiv : the preprint server for biology · 2026Article
- Neural geometry in the human hippocampus enables generalization across spatial position and gaze.ArXiv · 2026Article
- Non-Canonical Subiculum Circuit Organization and Function.Hippocampus · 2026Review
- Subicular Astrocytes Govern Seizure-Impaired Fear Memory.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A neural manifold view of the brain.Nature neuroscience · 2025Review
- Structural diversity inside the mouse subiculum revealed by a new marker protein fibronectin 1.Anatomical science international · 2025Article
- Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum.Communications biology · 2025Article
- The role of oscillations in grid cells' toroidal topology.PLoS computational biology · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The subiculum (SUB) plays a crucial role in spatial navigation and encodes navigational information differently from the hippocampal CA1 area. However, the representation of subicular population activity remains unknown. Here, we investigated the neuronal population activity recorded extracellularly from the CA1 and SUB of rats performing T-maze and open-field tasks. The trajectory of population activity in both areas was confined to low-dimensional neural manifolds homoeomorphic to external space. The manifolds conveyed position, speed, and future path information with higher decoding accuracy in the SUB than in the CA1. The manifolds exhibited common geometry across rats and regions for the CA1 and SUB and between tasks in the SUB. During post-task ripples in slow-wave sleep, population activity represented reward locations/events more frequently in the SUB than in CA1. Thus, the CA1 and SUB encode information distinctly into the neural manifolds that underlie navigational information processing during wakefulness and sleep.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.