Evidence map›Paper›PMID 38295172›Full record

ArticleScience advances2024

tPA-anchored nanorobots for in vivo arterial recanalization at submillimeter-scale segments.

Ben Wang, Qinglong Wang, Kai Fung Chan, Zhipeng Ning, Qianqian Wang, Fengtong Ji, Haojin Yang, Shuai Jiang, Zifeng Zhang, Bonaventure Yiu Ming Ip and 10 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Soft robotic devices for cardiovascular medicine.Nature reviews. Cardiology · 2026
    Review
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  19. Review
  20. Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 4 countries.

Ben WangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-7037-3660
Qinglong WangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0009-0008-4213-8506
Kai Fung ChanChow Yuk Ho Technology Center for Innovative Medicine, CUHK, Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-5820-0089
Zhipeng NingDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.
Qianqian WangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-8011-171X
Fengtong JiDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0002-9624-3503
Haojin YangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.
Shuai JiangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0002-4524-5939
Zifeng ZhangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-7096-7223
Bonaventure Yiu Ming IpDivision of Neurology, Department of Medicine and Therapeutics, CUHK, Sha Tin, N.T., Hong Kong, China.
Ho KoDivision of Neurology, Department of Medicine and Therapeutics, CUHK, Sha Tin, N.T., Hong Kong, China.ORCID 0000-0002-0254-3274
Jacqueline Pui Wah ChungDepartment of Obstetrics and Gynaecology, CUHK, Sha Tin, N.T., Hong Kong, China.
Ming QiuDepartment of Neurosurgery, South China Hospital of Shenzhen University, Shenzhen, China.
Jianguo HanDepartment of Neurosurgery, South China Hospital of Shenzhen University, Shenzhen, China.
Philip Wai Yan ChiuChow Yuk Ho Technology Center for Innovative Medicine, CUHK, Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-9292-112X
Joseph Jao Yiu SungLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0003-3125-5199
Shiwei DuDepartment of Neurosurgery, South China Hospital of Shenzhen University, Shenzhen, China.ORCID 0000-0001-9451-1204
Thomas Wai Hong LeungDivision of Neurology, Department of Medicine and Therapeutics, CUHK, Sha Tin, N.T., Hong Kong, China.ORCID 0000-0001-8193-0709
Simon Chun Ho YuDepartment of Imaging and Interventional Radiology, CUHK, Sha Tin, N.T., Hong Kong, China.ORCID 0000-0002-8715-5026
Li ZhangDepartment of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.ORCID 0000-0003-1152-8962
Chinese University of Hong Kong · HKShenzhen University · CNNanyang Technological University · SGShatin Hospital · CNSociety of Interventional Radiology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro/nanorobots provide a promising approach for intravascular therapy with high precision. However, blood vessel is a highly complex system, and performing interventional therapy in those submillimeter segments remains challenging. While micro/nanorobots can enter submillimeter segments, they may still comprise nonbiodegradable parts, posing a considerable challenge for post-use removal. Here, we developed a retrievable magnetic colloidal microswarm, composed of tPA-anchored Fe

Indexed as

ArteriesTissue Plasminogen ActivatorAnimalsHumansRabbitsTissue Plasminogen Activator

Identifiers

PMID38295172
PMCPMC10830105
OpenAlexW4391418294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.