Evidence map›Paper›PMID 38294928›Full record

ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2024

Fabrication and Validation of Sub-Cellular Carbon Fiber Electrodes.

Julianna Richie, Joseph G Letner, Autumn Mclane-Svoboda, Yu Huan, Dorsa Haji Ghaffari, Elena Della Valle, Paras R Patel, Hillel J Chiel, Galit Pelled, James D Weiland and 1 more

Open access · diamondAbstract read
In one paragraph

Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Julianna Richie
Joseph G Letner
Autumn Mclane-Svoboda
Yu Huan
Dorsa Haji Ghaffari
Elena Della Valle
Paras R Patel
Hillel J Chiel
Galit Pelled
James D Weiland
Cynthia A Chestek
University of Michigan · USCase Western Reserve University · USMichigan State University · US

Funding

Optimization and distribution of high density cellular scale carbon and silicon arraysUF1NS107659 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHESTEK, CYNTHIA ANNE · 2018 to 2018
$3.4M
Circuit dynamics of sensorimotor integration and decision making in octopusUF1NS115817 · NINDS · MICHIGAN STATE UNIVERSITY · PI PELLED, GALIT · 2020 to 2020
$2.3M
Intraretinal stimulation for high acuity artificial visionR01EY035008 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI James D Weiland · 2024 to 2026
$1.7M
A novel approach to analyzing functional connectomics and combinatorial control in a tractable small-brain closed-loop systemR01NS118606 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BYRNE, JOHN H, CHESTEK, CYNTHIA ANNE · 2023 to 2024
$1.7M
Neural Engineering Training Program (NETP)T32NS115724 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI James D Weiland · 2021 to 2026
$1.2M
NEI NIH HHS R01 EY035008NINDS NIH HHS R01 NS118606NINDS NIH HHS T32 NS115724NINDS NIH HHS UF1 NS107659NINDS NIH HHS UF1 NS115817
6 · The paper itself

Abstract

Multielectrode arrays for interfacing with neurons are of great interest for a wide range of medical applications. However, current electrodes cause damage over time. Ultra small carbon fibers help to address issues but controlling the electrode site geometry is difficult. Here we propose a methodology to create small, pointed fiber electrodes (SPFe). We compare the SPFe to previously made blowtorched fibers in characterization. The SPFe result in small site sizes [Formula: see text] with consistently sharp points (20.8 ± 7.64°). Additionally, these electrodes were able to record and/or stimulate neurons multiple animal models including rat cortex, mouse retina, Aplysia ganglia and octopus axial cord. In rat cortex, these electrodes recorded significantly higher peak amplitudes than the traditional blowtorched fibers. These SPFe may be applicable to a wide range of applications requiring a highly specific interface with individual neurons.

Indexed as

Cerebral CortexNeuronsAnimalsCarbon FiberElectrodesElectrodes, ImplantedMiceRatsCarbon Fiber

Identifiers

PMID38294928
PMCPMC10919889
OpenAlexW4391407071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.