Evidence map›Paper›PMID 38294622›Full record

ArticleJournal of assisted reproduction and genetics2024

Correlation of self-reported racial background to euploidy status and live birth rates in assisted reproductive technology cycles.

Tamar Alkon-Meadows, Carlos Hernandez-Nieto, Tia Jackson-Bey, Teresa A Cacchione, Joseph Lee, Martha Luna-Rojas, Dmitry Gounko, Alan Copperman, Erkan Buyuk

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tamar Alkon-MeadowsReproductive Medicine Associates of New York, New York, NY, USA. tamar.alkon@rmamexico.com.ORCID http://orcid.org/0000-0001-8866-8379
Carlos Hernandez-NietoReproductive Medicine Associates of New York, New York, NY, USA.
Tia Jackson-BeyReproductive Medicine Associates of New York, New York, NY, USA.
Teresa A CacchioneReproductive Medicine Associates of New York, New York, NY, USA.
Joseph LeeReproductive Medicine Associates of New York, New York, NY, USA.
Martha Luna-RojasReproductive Medicine Associates of New York, New York, NY, USA.
Dmitry GounkoReproductive Medicine Associates of New York, New York, NY, USA.
Alan CoppermanReproductive Medicine Associates of New York, New York, NY, USA.
Erkan BuyukReproductive Medicine Associates of New York, New York, NY, USA.
Reproductive Medicine Associates of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether the embryonic euploidy rate and live birth outcomes following single, euploid embryo transfer (SEET) differ among women of self-reported racial and ethnic backgrounds.

methodsThis retrospective cohort study included all infertile patients of different self-reported racial backgrounds who underwent In vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) and an autologous single euploid embryo transfer (SEET) from December 2015 to December 2019 at a single private and academic assisted reproduction technology center. Primary outcome measures included ploidy rates among different racial groups. Secondary outcomes included clinical pregnancy, clinical pregnancy loss, and live birth rates.

resultsFive thousand five hundred sixty-two patients who underwent an IVF cycle with ICSI-PGT-A were included. A total of 24,491 blastocysts were analyzed. White participants had on average more euploid embryos and higher euploidy rates when compared to their counterparts (p ≤ 0.0001). However, after controlling for confounding factors, there was no association between race and the odds of having  a higher euploidy rate (aOR 1.31; 95% CI 0.63-2.17, p = 0.42). A total of 4949 patients underwent SEET. Pregnancy outcomes did not differ among patients of varying self-reported races.

conclusionsEuploidy rates and pregnancy outcomes were comparable among patients of different racial backgrounds who underwent a SEET.

Indexed as

Birth RatePreimplantation DiagnosisAneuploidyBlastocystFemaleFertilization in VitroGenetic TestingHumansLive BirthPregnancyPregnancy RateRetrospective StudiesSelf ReportEuploidyIn vitro fertilizationLive birth ratePreimplantation genetic testingSelf-reported racial background

Identifiers

PMID38294622
PMCPMC10957844
OpenAlexW4391400147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.