Evidence map›Paper›PMID 38294241›Full record

ArticleInfection and immunity2024

IL-33-binding HpARI family homologues with divergent effects in suppressing or enhancing type 2 immune responses.

Florent Colomb, Adefunke Ogunkanbi, Abhishek Jamwal, Beverly Dong, Rick M Maizels, Constance A M Finney, James D Wasmuth, Matthew K Higgins, Henry J McSorley

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Dynamics of Interleukin-9 Producing Lymphocytes inPathogens (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Modulation of the Immune Response by Nematode Derived Molecules.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Florent Colomb *Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Adefunke Ogunkanbi *Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Abhishek Jamwal *Department of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0009-0004-6842-6056
Beverly DongDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Rick M MaizelsWellcome Centre for Integrative Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.
Constance A M FinneyDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-8459-8462
James D WasmuthHost-Parasite Interactions Research Training Network, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-9516-212X
Matthew K HigginsDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2870-1955
Henry J McSorleyDivision of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0003-1300-7407

Funding

Medical Research Council MR/S000593/2Medical Research Council UK MR/S000593/1Wellcome TrustWellcome Trust 221914/Z/20/Z
6 · The paper itself

Abstract

HpARI is an immunomodulatory protein secreted by the intestinal nematode

Indexed as

Nematospiroides dubiusStrongylida InfectionsAnimalsCytokinesImmunityImmunomodulationInterleukin-33MiceCytokinesInterleukin-33helminthIL-33immunomodulation

Identifiers

PMID38294241
PMCPMC10929406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.