Evidence map›Paper›PMID 38293997›Full record

ArticleAnnals of human biology2024

Body composition after implementation of an enhanced parenteral nutrition protocol in the neonatal intensive care unit: a randomised pilot trial.

Emily M Nagel, Jennifer Super, Nicholas A Marka, Ellen W Demerath, Sara E Ramel

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of human biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. [Expert consensus on parenteral nutrition management in neonates (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emily M NagelDivision of Epidemiology and Community Health, School of Public Health, University of MN, Minneapolis, MN, USA.ORCID 0000-0002-5792-009X
Jennifer SuperDepartment of Pediatrics, Division of Neonatology, School of Medicine, University of Minnesota, Minneapolis, MN, USA.
Nicholas A MarkaClinicial and Translational Science Institute, University of Minnesota, Minneapolis, MN, USA.
Ellen W DemerathDivision of Epidemiology and Community Health, School of Public Health, University of MN, Minneapolis, MN, USA.
Sara E RamelDepartment of Pediatrics, Division of Neonatology, School of Medicine, University of Minnesota, Minneapolis, MN, USA.
University of Minnesota · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Minnesota Obesity Prevention Training (MnOPT)T32DK083250 · NIDDK · UNIVERSITY OF MINNESOTA · PI KOTZ, CATHERINE M, LASKA, MELISSA N. · 2010 to 2024
$5.1M
Maternal Stress, Human Milk Composition, and Neurodevelopmental and Feeding OutcomesK99HD108276 · NICHD · UNIVERSITY OF MINNESOTA · PI NAGEL, EMILY M · 2022 to 2023
$245k
NCATS NIH HHS UL1 TR002494NICHD NIH HHS K99 HD108276NIDDK NIH HHS T32 DK083250
6 · The paper itself

Abstract

backgroundVery low birthweight (VLBW) infants are at risk for growth failure and poor neurodevelopment. Optimised parenteral nutrition may help promote optimal growth and development, but concerns that provision of enhanced nutrition may contribute to increased early adiposity and later metabolic disease remain.

aimTo determine associations between provision of an early enhanced parenteral nutrition protocol or standard parenteral nutrition protocol and growth and body composition for VLBW preterm infants in the neonatal intensive care unit. SUBJECTS: This is a secondary analysis of data from a clinical trial aimed at assessing the feasibility and safety of randomising VLBW preterm infants to Standard (

methodsWe evaluated associations between weekly infant growth and body composition measurements from

resultNo statistically significant associations between nutrition group and infant growth or body composition measures were observed (

conclusionIn this pilot trial, enhanced parenteral nutrition in the first week of life was not associated with significant differences in infant growth or body composition during hospitalisation.

Indexed as

Infant, PrematureIntensive Care Units, NeonatalBody CompositionHumansInfantInfant, NewbornInfant, Very Low Birth WeightParenteral NutritionPilot ProjectsRandomized Controlled Trials as Topicenhanced nutritionparenteral nutritionPrematurity

Identifiers

PMID38293997
PMCPMC10964316
OpenAlexW4391387854

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.