Evidence map›Paper›PMID 38293981›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Validation of a C57/BL6J mouse model of focal cerebral ischemia established by electrocoagulation of the middle cerebral artery].

Y Kang, D Tang, J Zhang, Q Xia

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Y KangResearch Center of Experimental Acupuncture, Tianjin University of Chinese Medicine, Tianjin 301617, China.
D TangResearch Center of Experimental Acupuncture, Tianjin University of Chinese Medicine, Tianjin 301617, China.
J ZhangResearch Center of Experimental Acupuncture, Tianjin University of Chinese Medicine, Tianjin 301617, China.
Q XiaResearch Center of Experimental Acupuncture, Tianjin University of Chinese Medicine, Tianjin 301617, China.
Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo modify the method for establishing mouse models of middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia using electrocoagulation.

methodsForty-six C57/BL6J male mice were divided into MCAO model group (

resultsThe mice in the model group showed significantly reduced cerebral blood flow in the MCA on the ischemic side and obvious neurological deficits with increased forelimb use asymmetry on days 1, 7 and 14 after modeling (

conclusionWe successfully prepared mouse models of MCAO using a modified method by changing the electrocoagulation location from the distal location of the junction between the MCA and the inferior cerebral vein to a 2 mm segment medial to the junction between the MCA and the olfactory bundle.

Indexed as

Brain IschemiaMiddle Cerebral ArteryAnimalsBrain-Derived Neurotrophic FactorDisease Models, AnimalInfarction, Middle Cerebral ArteryMaleMiceStaining and LabelingBrain-Derived Neurotrophic Factorcerebral ischemic miceelectrocoagulationevaluation indicatorsmiddle cerebral artery

Identifiers

PMID38293981
PMCPMC10878904
OpenAlexW4394759304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.