ArticleBMJ medicine2024
Post-covid-19 conditions in adults: systematic review and meta-analysis of health outcomes in controlled studies.
Article in BMJ medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Post-COVID syndrome in Pakistan, India, and Bangladesh: a systematic narrative review of epidemiology, clinical manifestations, and healthcare system responses.Frontiers in public health · 2026Pooled it
- Effects of exercise programs on cardiopulmonary function and signs and symptoms in patients with post-COVID-19 condition: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Meta-analysis of Cognitive Function Following Non-severe SARS-CoV-2 Infection.Neuropsychology review · 2025Pooled it
- Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Brief Outpatient Rehabilitation Program for Post-COVID-19 Condition: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Risk factors of post-COVID-19 symptoms, a cross-sectional study in patients with asthma and chronic obstructive lung disease.NPJ primary care respiratory medicine · 2026Article
- Towards a Less Ideal Theory About Well-being-The Case of Post COVID Condition.Journal of bioethical inquiry · 2026Article
- Long-term health outcomes and risk factors for low self-rated health in non-hospitalised adults with post-COVID-19 condition: a 2.5-year cohort study.BMC public health · 2026Article
- Article
- Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study.Einstein (Sao Paulo, Brazil) · 2026Article
- REGENECYTE cord blood cell therapy in post-COVID syndrome: a phase IIa randomized, placebo-controlled trial.EClinicalMedicine · 2026Article
- German nationwide inpatient data on the post-COVID-19 syndrome: an update.Frontiers in public health · 2026Article
- Long COVID in adults - a current review of the long-term health effects following SARS-CoV-2 infection.Journal of health monitoring · 2026Article
- Barriers to Mobility in the ICU: Insights from Severe COVID-19 and Implications for Improving Patient Outcomes.Archives of rehabilitation research and clinical translation · 2025Article
- Impact of COVID-19 on Health-Related Quality of Life and Mental Health Among Employees in Health and Social Services-A Longitudinal Study.Infectious disease reports · 2025Article
- Article
- Health-related quality of life related to diabetes multisensory deficits and derealization.Scientific reports · 2025Article
- COVID-19 infection history as a risk factor for early pregnancy loss: results from the electronic health record-based Southeast Texas COVID and Pregnancy Cohort Study.BMC medicine · 2025Article
- Social Vulnerability and Long-Term Cardiovascular Outcomes After COVID-19 Hospitalization: An Analysis of the American Heart Association COVID-19 Registry Linked With Medicare Claims Data.Journal of the American Heart Association · 2025Article
- Determination of both the expression and serum levels of epidermal growth factor and transforming growth factor β1 genes in COVID-19.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To assess the impact of post-covid-19 conditions among adults. Design: Systematic review and meta-analysis of health outcomes in controlled studies. Data sources: Two sources were searched from database inception to 20 October 2022: Cochrane covid-19 study register (comprising Cochrane Central Register of Controlled Trials, Medline, Embase, clinicalTrials.gov, World Health Organization's International Clinical Trials Registry Platform, medRxiv) and WHO's covid-19 research database. Eligibility criteria: Cohort studies recruiting more than 100 participants with a control group and a follow-up of at least 12 weeks were included. Adults who were documented to have SARS-CoV-2 infection based on clinical, imaging, or laboratory criteria were included. Data extraction and synthesis: Two independent reviewers extracted data. The main outcomes included quality of life, functionality in daily activities, use of resources, recovery rates (cluster of symptoms), and the incidence of new medical diagnoses. Data were pooled using a random effects model. The risk of bias was assessed with the Joanna Briggs Institute critical appraisal tool for cohort studies. Results: We included 63 controlled cohort studies, encompassing more than 96 million participants. Based on five studies, we found a reduction in overall quality of life between individuals with confirmed SARS-CoV-2 infection versus controls at six to 24 months follow-up, although heterogeneity was very high (mean difference in EQ-5D scale -5.28 (95% confidence interval -7.88 to 2.68; I Conclusion: Evidence suggests functional impairment after SARS-CoV-2 infection, in addition to a higher use of resources and a higher incidence of widely varying medical diagnoses. These results should be interpreted with caution, considering the high heterogeneity across studies and study limitations related to outcome measurement and attrition of participants. Systematic review registration: Open Science Framework, osf.io/drm39.
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