Evidence map›Paper›PMID 38293221›Full record

ArticlebioRxiv : the preprint server for biology2024

Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2.

Pritesh Desai, Courtney E Karl, Baoling Ying, Chieh-Yu Liang, Tamara Garcia-Salum, Ana Carolina Santana, Felipe Ten Caten, Joseph F Urban, Sayda M Elbashir, Darin K Edwards and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Pritesh DesaiDepartment of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.
Courtney E KarlDepartment of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.
Baoling YingDepartment of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.
Chieh-Yu LiangDepartment of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.
Tamara Garcia-SalumDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Ana Carolina SantanaDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Felipe Ten CatenDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Joseph F UrbanUS Department of Agriculture, Agricultural Research Services, Beltsville Human Nutrition Research Center, Diet, Genomics, and Immunology Laboratory, and Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705-2350, USA.
Sayda M ElbashirModerna, Inc., Cambridge, MA, USA.
Darin K EdwardsModerna, Inc., Cambridge, MA, USA.
Susan P RibeiroDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Larissa B ThackrayDepartment of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.
Rafick P SekalyDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Michael S DiamondDepartment of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-8791-3165
Washington University in St. Louis · USEmory University · USModerna Therapeutics (United States) · USAgricultural Research Service · US

Funding

COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4M
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6M
Human antibody-based countermeasures against the Wuhan Coronavirus SARS-CoV-2R01AI157155 · NIAID · WASHINGTON UNIVERSITY · PI BARIC, RALPH S, CROWE, JAMES E · 2020 to 2024
$6.0M
NIAID NIH HHS 75N93019C00051NIAID NIH HHS 75N93021C00014NIAID NIH HHS R01 AI157155
6 · The paper itself

Abstract

Although vaccines have reduced COVID-19 disease burden, their efficacy in helminth infection endemic areas is not well characterized. We evaluated the impact of infection by

Identifiers

PMID38293221
PMCPMC10827110
OpenAlexW4390893365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.