Evidence map›Paper›PMID 38293203›Full record

ArticlebioRxiv : the preprint server for biology2025

Macrophage-induced reduction of bacteriophage density limits the efficacy of

Sophia Zborowsky, Jérémy Seurat, Quentin Balacheff, Solène Ecomard, Céline Mulet, Chau Nguyen Ngoc Minh, Marie Titécat, Emma Evrard, Rogelio A Rodriguez-Gonzalez, Jacopo Marchi and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Sophia ZborowskyInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0000-0002-4899-3975
Jérémy SeuratInstitut de Biologie, Ecole Normale Supérieure, Paris 75005, France.ORCID 0000-0002-8127-7751
Quentin BalacheffInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0000-0002-6305-8256
Solène EcomardInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0009-0007-9316-9671
Céline MuletInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.
Chau Nguyen Ngoc MinhInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0009-0003-2180-864X
Marie TitécatUniversité de Lille, INSERM, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, Lille 59000, France.ORCID 0000-0002-5860-0936
Emma EvrardInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0009-0003-6502-4775
Rogelio A Rodriguez-GonzalezSchool of Biological Sciences, Georgia Institute of Technology, Atlanta GA 30332, USA.ORCID 0000-0002-5460-4999
Jacopo MarchiSchool of Biological Sciences, Georgia Institute of Technology, Atlanta GA 30332, USA.ORCID 0000-0003-1192-1203
Joshua S WeitzInstitut de Biologie, Ecole Normale Supérieure, Paris 75005, France.ORCID 0000-0002-3433-8312
Laurent DebarbieuxInstitut Pasteur, Université Paris Cité, Bacteriophage Bacterium Host, Paris 75015, France.ORCID 0000-0001-6875-5758
Institut Pasteur · FRGeorgia Institute of Technology · USInserm · FR

Funding

Synergistic control of acute respiratory pathogens by bacteriophage and the innate immune responseR01AI146592 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI DEBARBIEUX, LAURENT, WEITZ, JOSHUA · 2019 to 2023
$2.4M
NIAID NIH HHS R01 AI146592
6 · The paper itself

Abstract

The rise of antimicrobial resistance has led to renewed interest in evaluating phage therapy. In murine models highly effective treatment of acute pneumonia caused by

Indexed as

Antimicrobial resistanceBacterial infectionInnate immunityMathematical modelPneumonia

Identifiers

PMID38293203
PMCPMC10827109
OpenAlexW4390928470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.