Evidence map›Paper›PMID 38293157›Full record

ArticlebioRxiv : the preprint server for biology2024

Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis.

Divyesh Joshi, Brian G Coon, Raja Chakraborty, Hanqiang Deng, Pablo Fernandez-Tussy, Emily Meredith, James G Traylor, Anthony Wayne Orr, Carlos Fernandez-Hernando, Martin A Schwartz

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Divyesh JoshiYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-4415-2677
Brian G CoonYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.
Raja ChakrabortyYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.
Hanqiang DengYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.ORCID 0000-0001-5976-517X
Pablo Fernandez-TussyVascular Biology and Therapeutics Program, Yale University, New Haven, CT 06520, USA.
Emily MeredithYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.
James G TraylorDepartment of Pathology and Translational Pathobiology, LSU Health Shreveport, LA 71103, USA.
Anthony Wayne OrrDepartment of Pathology and Translational Pathobiology, LSU Health Shreveport, LA 71103, USA.
Carlos Fernandez-HernandoVascular Biology and Therapeutics Program, Yale University, New Haven, CT 06520, USA.
Martin A SchwartzYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06511, USA.
Yale University · USLouisiana State University Health Sciences Center Shreveport · US

Funding

Integrins in the Endothelial Response to Fluid Shear StressR01HL075092 · NHLBI · YALE UNIVERSITY · PI SCHWARTZ, MARTIN A · 2004 to 2019
$5.1M
NHLBI NIH HHS R01 HL075092
6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality worldwide

Indexed as

fluid shear stressmechanotransductionprotocadherin gamma A9vascular inflammation

Identifiers

PMID38293157
PMCPMC10827163
OpenAlexW4390936952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.