Evidence map›Paper›PMID 38293063›Full record

ArticlebioRxiv : the preprint server for biology2024

Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in

Susu He, Noor M Taher, Kelli L Hvorecny, Michael J Ragusa, Christopher D Bahl, Alison B Hickman, Fred Dyda, Dean R Madden

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Susu HeDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0002-2138-3421
Noor M TaherDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0001-8783-120X
Kelli L HvorecnyDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0002-4609-6170
Michael J RagusaDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0002-0231-0876
Christopher D BahlDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0002-3652-3693
Alison B HickmanLaboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892 USA.ORCID 0000-0001-7666-0249
Fred DydaLaboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892 USA.ORCID 0000-0003-1689-9041
Dean R MaddenDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 USA.ORCID 0000-0002-1810-6984

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MIERKE, DALE F · 2016 to 2025
$25.9M
Life Science and Biomedical technology Research center at NSLS-II LSBRP41GM111244 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MCSWEENEY, SEAN · 2014 to 2018
$16.4M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Molecular and Cellular Biology at DartmouthT32GM008704 · NIGMS · DARTMOUTH COLLEGE · PI COMPTON, DUANE A. · 1998 to 2018
$6.8M
Dissecting the Molecular Mechanisms of Selective AutophagyR35GM128663 · NIGMS · DARTMOUTH COLLEGE · PI Michael Joseph Ragusa · 2018 to 2026
$3.5M
Mechanism of Cif Virulence: A Bacterial Strategy to Subvert Host-Cell DefensesR01AI091699 · NIAID · DARTMOUTH COLLEGE · PI MADDEN, DEAN R, O'TOOLE, GEORGE A. · 2012 to 2016
$2.3M
A Simultaneous SAXS/WAXS Detector System for Solving Biological StructuresS10OD012331 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI ALLAIRE, MARC · 2012 to 2012
$1.1M
NIAID NIH HHS R01 AI091699NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM113132NIGMS NIH HHS P41 GM103393NIGMS NIH HHS P41 GM111244NIGMS NIH HHS R35 GM128663NIGMS NIH HHS T32 GM008704NIGMS NIH HHS Y01 GM000080NIH HHS S10 OD012331
6 · The paper itself

Abstract

The opportunistic pathogen

Indexed as

Epoxide-based virulence circuitProtein-DNA recognitionPseudomonas aeruginosaTetR family transcriptional regulators (TFRs)X-ray crystallography

Identifiers

PMID38293063
PMCPMC10827105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.