ReviewCureus2023
Success and Complication Rates of Revascularization Procedures for Immature Necrotic Teeth: A Systematic Review.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 8 citations in OpenAlex.
- Modified apexification with MTA and non-vital bleaching as a comprehensive case management of a necrotic immature tooth: A case report.BMC oral health · 2026Article
- Fracture resistance of regenerated immature teeth in different simulated stages of root development: an in vitro cyclic loading study.Restorative dentistry & endodontics · 2026Article
- Age-driven dysbiosis: gut microbiota in the pathogenesis and treatment of aging disorders.Biogerontology · 2026Review
- Redefining regeneration: proposal of a radiographic outcome-based framework for evaluating regenerative endodontic procedures in immature necrotic teeth.Biomaterial investigations in dentistry · 2026Article
- Clinical efficacy and prognostic factors of regenerative endodontic procedure for immature permanent teeth with periapical periodontitis.Frontiers in medicine · 2026Article
- Enhanced Recovery After Surgery Reduces Complications and Length of Stay in Metabolic and Bariatric Surgery: A 1,800-Patient Middle Eastern Study.Obesity surgery · 2025Article
- Advanced Platelet-Rich Fibrin Plus Sealed Exclusively with Glass Ionomer Cement: Setting a New Standard for Healing, Aesthetics and Predictive Modelling in Regenerative Endodontics.Materials (Basel, Switzerland) · 2025Article
- Regenerative Endodontic Procedure of a Mature Anterior Tooth With Open Apex and Chronic Apical Abscess: A Case Report With 4-Years Follow-Up.Clinical case reports · 2025Article
- Managing a Complicated Crown Fracture of a Central Incisor: A Case Report With 1-Year Follow-Up.Clinical case reports · 2025Article
- Article
- Management Strategies for Immature Teeth with Pulp Necrosis: An Umbrella Review of Systematic Reviews.Iranian endodontic journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frequently, adolescents exhibit instances of immature necrotic teeth, which are identifiable by their slender root walls and unclosed root tips. The lack of a natural narrowing near the root's end creates difficulty when using standard endodontic procedures, making the effective sealing of the immature root canal difficult or impractical. Revascularization therapy surfaces as a prospective strategy for addressing the management of undeveloped, non-vital, immature, necrotic teeth. Notwithstanding this, apexification continues to hold prominence in the preferences of clinicians owing to its perceived predictability in treatment outcomes. A systematic investigation was conducted involving various search engines and databases, covering the period from 2001 to 2023. The main aim of this investigation was to find randomized clinical trials that compared the efficacy of revascularization therapy to apexification for treating immature necrotic teeth. The evaluation included a thorough examination of both clinical and radiographic outcomes assessing the success rates and complications. Out of the 850 identified articles, 15 studies were chosen for comprehensive analysis. Notable dissimilarities were not identified between the revascularization therapy and apexification groups concerning parameters such as rates of periapical healing, overall effectiveness/invalidation, and apical closure. However, concentrating on measurable factors, it became clear that the revascularization treatment group displayed a notable rise in root length compared to the apexification group. Both revascularization endodontic therapy and apexification demonstrated effectiveness in addressing periapical periodontitis healing and open apex closure. Pulp revascularization stood out for its notable efficacy in enhancing root elongation and thickening, all while having a reduced likelihood of treatment being deemed ineffective overall.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.