Evidence map›Paper›PMID 38292932›Full record

ArticleBone reports2024

Hyoid bone morphology in patients with isolated robin sequence - A case-control study utilizing 3D morphable models.

C P O M Van Den Berg, K El Ghoul, E O'Sullivan, P K Guntaka, C M Resnick, B Pullens, R H Khonsari, D J Dunaway, E B Wolvius, L S Van de Lande and 1 more

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In one paragraph

Article in Bone reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

C P O M Van Den BergDepartment of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
K El GhoulDepartment of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
E O'SullivanDepartment of Computing, Imperial College London, London, United Kingdom.
P K GuntakaDepartment of Plastic and Oral Surgery, Boston Children's Hospital, Boston, United States of America.
C M ResnickDepartment of Plastic and Oral Surgery, Boston Children's Hospital, Boston, United States of America.
B PullensDepartment of Otorhinolaryngology, Erasmus University Medical Center, Rotterdam, the Netherlands.
R H KhonsariService de Chirurgie Maxillofaciale et Chirurgie Plastique, Hôpital Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris, Faculté de Médecine, Université Paris Cité, Paris, France.
D J DunawayCraniofacial Unit, University College London, Great Ormond Street Hospital, London, United Kingdom.
E B WolviusDepartment of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
L S Van de LandeDepartment of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
M J KoudstaalDepartment of Oral and Maxillofacial Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NLGreat Ormond Street Hospital · GBBoston Children's Hospital · USBoston University · USImperial College London · GBUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Abnormalities of the hyoid bone are associated with impairment of oropharyngeal functions including feeding, swallowing, and breathing. Few studies have characterized anatomic abnormalities of the hyoid in patients with Robin sequence (RS), e.g. a less mineralized and voluminous hyoid. The purpose of this study was to compare normal hyoid bone morphology and hyoid bone morphology in children with isolated RS. Methods: Three-dimensional (3D) reconstructions of the hyoid bone were obtained from CT-imaging of children with RS and unaffected controls. A 3D morphable model was constructed using Principal Component Analysis (PCA). Partial least squares - Discriminant Analysis (PLS-DA) and multivariate analysis of variance (MANOVA) were used to characterize and compare hyoid shape differences between patients with RS and an age-matched control group. Results: The study included 23 subjects with RS (mean age 9.8 ± 10.3 months) and 46 age-matched control samples. A less voluminous hyoid was observed for the RS group with a larger lateral divergence of the greater horns compared to controls (MANOVA, Conclusions: The 3D morphable models provide a comprehensive and quantitative description of variation in normal hyoid bone morphology, and allow detection of distinct differences between patients with isolated RS and controls.

Indexed as

Geometric morphometricsHyoid boneOropharyngeal impairmentRobin sequenceShape analysis

Identifiers

PMID38292932
PMCPMC10827493
OpenAlexW4390871236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.