ArticleWorld journal of clinical cases2024
Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis.
Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies.Frontiers in medicine · 2026Pooled it
- Supraventricular Tachycardia Ablation in the Elderly-Characteristics and Outcomes.Journal of arrhythmia · 2026Article
- Frailty Trajectories and Determinants in Older Adults After PCI: A Longitudinal Study.Clinical interventions in aging · 2026Observational
- Article
- Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction.World journal of cardiology · 2025Article
- Optimizing Angioplasty in Elderly Patients with Multimorbidity: A Paradigm Shift in Risk Assessment: Optimizing Angioplasty in Elderly Patients with Multimorbidity.Galen medical journal · 2025Article
- Fragile hearts: Unveiling the crucial layers of frailty in elderly patients undergoing percutaneous coronary interventions.World journal of clinical cases · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is a common condition in elderly patients who receive percutaneous coronary intervention (PCI). However, how frailty affects clinical outcomes in this group is unclear.
aimTo assess the link between frailty and the outcomes, such as in-hospital complications, post-procedural complications, and mortality, in elderly patients post-PCI.
methodsThe PubMed/MEDLINE, EMBASE, Cochrane Library, and Web of Science databases were screened for publications up to August 2023. The primary outcomes assessed were in-hospital and all-cause mortality, major adverse cardiovascular events (MACEs), and major bleeding. The Newcastle-Ottawa Scale was used for quality assessment.
resultsTwenty-one studies with 739693 elderly patients undergoing PCI were included. Frailty was consistently associated with adverse outcomes. Frail patients had significantly higher risks of in-hospital mortality [risk ratio: 3.45, 95% confidence interval (95%CI): 1.90-6.25], all-cause mortality [hazard ratio (HR): 2.08, 95%CI: 1.78-2.43], MACEs (HR: 2.92, 95%CI: 1.85-4.60), and major bleeding (HR: 4.60, 95%CI: 2.89-7.32) compared to non-frail patients.
conclusionFrailty is a pivotal determinant in the prediction of risk of mortality, development of MACEs, and major bleeding in elderly individuals undergoing percutaneous coronary intervention.
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