Evidence map›Paper›PMID 38292453›Full record

ArticleFrontiers in cardiovascular medicine2023

Gender disparities in patients undergoing extracorporeal cardiopulmonary resuscitation.

A Springer, A Dreher, J Reimers, L Kaiser, E Bahlmann, H van der Schalk, P Wohlmuth, N Gessler, K Hassan, J Wietz and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

A SpringerDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
A DreherDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
J ReimersDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
L KaiserDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
E BahlmannDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
H van der SchalkDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
P WohlmuthAsklepios ProResearch, Hamburg, Germany.
N GesslerDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
K HassanDepartment of Cardiac Surgery, Asklepios Clinic St. Georg, Hamburg, Germany.
J WietzDepartment of Emergency Medicine, Asklepios Clinic St. Georg, Hamburg, Germany.
B BeinDepartment of Anaesthesiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
T SpangenbergDepartment of Cardiology and Critical Care, Asklepios Clinic Altona, Hamburg, Germany.
S WillemsDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
S HakmiDZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany.
E TiggesDepartment of Cardiology and Critical Care, Asklepios Clinic St. Georg, Hamburg, Germany.
Asklepios Klinik St. Georg · DEAsklepios · DEAsklepios Klinik Altona · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in extracorporeal cardiopulmonary resuscitation (eCPR) has emerged as a treatment option for selected patients who are experiencing refractory cardiac arrest (CA). In the light of increasing availability, the analyses of outcome-relevant predisposing characteristics are of growing importance. We evaluated the prognostic influence of gender in patients presenting with out-of-hospital cardiac arrest (OHCA) treated with eCPR. Methods: We retrospectively analysed the data of 377 consecutive patients treated for OHCA using eCPR in our cardiac arrest centre from January 2016 to December 2022. The primary outcome was defined as the survival of patients until they were discharged from the hospital, with a favourable neurological outcome [cerebral performance category (CPC) score of ≤2]. Statistical analyses were performed using baseline comparison, survival analysis, and multivariable analyses. Results: Out of the 377 patients included in the study, 69 (21%) were female. Female patients showed a lower prevalence rate of pre-existing coronary artery disease (48% vs. 75%, Conclusion: Our analysis suggests a significant survival benefit for female patients who obtain eCPR, possibly driven by a higher prevalence of witnessed collapse and bystander CPR. Interestingly, the impact of patient age and BMI on neurologically favourable outcome was higher in female patients than in male patients, warranting further investigation.

Indexed as

CPReCPRgenderOHCAVA-ECMO

Identifiers

PMID38292453
PMCPMC10824923
OpenAlexW4390917290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.