Evidence map›Paper›PMID 38292327›Full record

ArticleMedComm2024

Repurposing iron chelators for accurate positron emission tomography imaging tracking of radiometal-labeled cell transplants.

Qian Xu, Xinyu Wang, Ziqian Mu, Yixiang Zhou, Xiang Ding, Xin Ji, Junjie Yan, Donghui Pan, Chongyang Chen, Yuping Xu and 4 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. CD24 as a Novel Radiopharmaceutical Target for Hepatocellular Carcinoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  2. Efficient radiolabeling of mesoporous silica nanoparticles for single-cell PET imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Qian XuDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Xinyu WangDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Ziqian MuDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Yixiang ZhouDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Xiang DingDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Xin JiNHC Key Laboratory of Nuclear Medicine Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi China.
Junjie YanDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Donghui PanNHC Key Laboratory of Nuclear Medicine Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi China.
Chongyang ChenNHC Key Laboratory of Nuclear Medicine Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi China.
Yuping XuDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Lizhen WangNHC Key Laboratory of Nuclear Medicine Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi China.
Jing WangJiangsu Renocell Biotech Co., Ltd. Nanjing China.
Guangji WangKey Laboratory of Drug Metabolism and Pharmacokinetics State Key Laboratory of Natural Medicines China Pharmaceutical University Nanjing China.
Min YangDepartment of Radiopharmaceuticals School of Pharmacy Nanjing Medical University Nanjing China.
Key Laboratory of Nuclear Radiation and Nuclear Energy Technology · CNNanjing Medical University · CNState Key Laboratory of Natural MedicineViva Biotech (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of radiolabeled cells for positron emission tomography (PET) imaging tracking has been a promising approach for monitoring cell-based therapies. However, the presence of free radionuclides released from dead cells during tracking can interfere with the signal from living cells, leading to inaccurate results. In this study, the effectiveness of the iron chelators deferoxamine (DFO) and deferiprone in removing free radionuclides

Indexed as

cell therapycell trackingiron chelatorPET imagingradiolabel

Identifiers

PMID38292327
PMCPMC10827001
OpenAlexW4391338383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.