Evidence map›Paper›PMID 38291839›Full record

ArticleMovement disorders clinical practice2024

The Optimal Targeting for Focused Ultrasound Thalamotomy Differs between Dystonic and Essential Tremor: A 12-Month Prospective Pilot Study.

Nico Golfrè Andreasi, Arianna Braccia, Vincenzo Levi, Sara Rinaldo, Francesco Ghielmetti, Roberto Cilia, Luigi Michele Romito, Salvatore Bonvegna, Antonio Emanuele Elia, Grazia Devigili and 15 more

Open access · hybridAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 3 institutions in 2 countries.

Nico Golfrè AndreasiParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0003-3555-5367
Arianna BracciaParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0003-1119-7518
Vincenzo LeviFunctional Neurosurgery Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0003-2713-6357
Sara RinaldoParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0002-5945-132X
Francesco GhielmettiHealth Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0003-2183-5077
Roberto CiliaParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0002-1990-1939
Luigi Michele RomitoParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0002-6772-1035
Salvatore BonvegnaParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0003-1772-5801
Antonio Emanuele EliaParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0002-5917-7578
Grazia DevigiliParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0001-9688-4231
Roberta TeleseParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0001-8099-3142
Fabiana ColucciParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0003-1945-8153
Maria Grazia BruzzoneNeuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0002-2786-1471
Giuseppe MessinaFunctional Neurosurgery Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0003-1060-1486
Marta CorradiParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0001-5121-5552
Mario StanzianoNeuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0002-5843-0965
Valentina CaldieraDiagnostic Radiology and Interventional Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0003-3105-3343
Sara PrioniClinical Neuropsychology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0001-9632-0591
Paolo AmamiClinical Neuropsychology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0001-8930-0293
Marco Fusar PoliClinical Neuropsychology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0009-0005-8201-1268
Sylvie Hélène Marie Jeanne PiacentiniClinical Neuropsychology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0003-2640-3281
Marina GrisoliNeuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0002-7663-446X
Elisa Francesca Maria CiceriDiagnostic Radiology and Interventional Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0002-6716-2923
Francesco DiMecoDepartment of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.ORCID 0000-0001-6213-5793
Roberto EleopraParkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Best, Milano, Italy.ORCID 0000-0002-6035-9715
Fondazione IRCCS Istituto Neurologico Carlo Besta · ITJohns Hopkins University · USNeuroscience Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is increasingly used to treat drug-resistant essential tremor (ET). Data on MRgFUS thalamotomy in dystonic tremor (DT) are anecdotal.

objectivesTo investigate efficacy, safety, and differences in target coordinates of MRgFUS thalamotomy in DT versus ET.

methodsTen patients with DT and 35 with ET who consecutively underwent MRgFUS thalamotomy were followed for 12 months. Although in both groups the initial surgical planning coordinates corresponded to the ventralis intermediate (Vim), the final target could be modified intraoperatively based on clinical response.

resultsTremor significantly improved in both groups. The thalamic lesion was significantly more anterior in DT than ET. Considering both ET and DT groups, the more anterior the lesion, the lower the odds ratio for adverse events.

conclusionsMRgFUS thalamotomy is safe and effective in DT and ET. Compared to classical Vim coordinates used for ET, more anterior targeting should be considered for DT.

Indexed as

Essential TremorHumansPilot ProjectsProspective StudiesThalamusTremordystoniadystonic tremoressential tremorMRgFUSthalamotomy

Identifiers

PMID38291839
PMCPMC10828621
OpenAlexW4387907416

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.