Evidence map›Paper›PMID 38291666›Full record

ArticleJournal of medicinal chemistry2024

Ir(III) Half-Sandwich Photosensitizers with a π-Expansive Ligand for Efficient Anticancer Photodynamic Therapy.

Carlos Gonzalo-Navarro, Elisenda Zafon, Juan Angel Organero, Félix A Jalón, Joao Carlos Lima, Gustavo Espino, Ana María Rodríguez, Lucía Santos, Artur J Moro, Sílvia Barrabés and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. DNA-Binding Properties of Iridium(III) Complexes Encompassing Design, Function and Biophysical Assessments.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Review
  5. Iminopyridonato Iridium Complexes:Inorganic chemistry · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Carlos Gonzalo-NavarroDepartamento de Química Inorgánica, Orgánica y Bioquímica- IRICA, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, Avda. C. J. Cela, 10, 13071 Ciudad Real, Spain.ORCID 0000-0001-6885-2427
Elisenda ZafonDepartament de Biologia, Facultat de Ciències, Universitat de Girona, Maria Aurèlia Capmany 40, 17003 Girona, Spain.
Juan Angel OrganeroDepartamento de Química Física, Facultad de Ciencias Ambientales y Bioquímicas and INAMOL, Universidad de Castilla-La Mancha, 45071 Toledo, Spain.
Félix A JalónDepartamento de Química Inorgánica, Orgánica y Bioquímica- IRICA, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, Avda. C. J. Cela, 10, 13071 Ciudad Real, Spain.ORCID 0000-0002-6622-044X
Joao Carlos LimaLAQV-REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.ORCID 0000-0003-0528-1967
Gustavo EspinoDepartamento de Química, Facultad de Ciencias, Universidad de Burgos, Pza. Misael Bañuelos, s/n, 09001 Burgos, Spain.ORCID 0000-0001-5617-5705
Ana María RodríguezDepartamento de Química Inorgánica, Orgánica y Bioquímica- IRICA, Escuela Técnica Superior de Ingenieros Industriales, Universidad de Castilla-La Mancha, Avda. C. J. Cela, 3, 13071 Ciudad Real, Spain.
Lucía SantosDepartamento de Química Física, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, Avda. C. J. Cela, s/n, 13071 Ciudad Real, Spain.
Artur J MoroLAQV-REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.ORCID 0000-0003-3285-4919
Sílvia BarrabésDepartament de Biologia, Facultat de Ciències, Universitat de Girona, Maria Aurèlia Capmany 40, 17003 Girona, Spain.ORCID 0000-0001-7004-0057
Jessica CastroDepartament de Biologia, Facultat de Ciències, Universitat de Girona, Maria Aurèlia Capmany 40, 17003 Girona, Spain.
Javier Camacho-AguayoAnalytical Chemistry Department, Analytic Biosensors Group, Instituto de Nanociencia y Nanomateriales de Aragon, Faculty of Sciences, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-1654-3803
Anna MassaguerDepartament de Biologia, Facultat de Ciències, Universitat de Girona, Maria Aurèlia Capmany 40, 17003 Girona, Spain.ORCID 0000-0003-1312-593X
Blanca R ManzanoDepartamento de Química Inorgánica, Orgánica y Bioquímica- IRICA, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, Avda. C. J. Cela, 10, 13071 Ciudad Real, Spain.ORCID 0000-0002-4908-4503
Gema DuráDepartamento de Química Inorgánica, Orgánica y Bioquímica- IRICA, Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, Avda. C. J. Cela, 10, 13071 Ciudad Real, Spain.
University of Castilla-La Mancha · ESUniversitat de Girona · ESRede de Química e Tecnologia · PTUniversidad de Burgos · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One approach to reduce the side effects of chemotherapy in cancer treatment is photodynamic therapy (PDT), which allows spatiotemporal control of the cytotoxicity. We have used the strategy of coordinating π-expansive ligands to increase the excited state lifetimes of Ir(III) half-sandwich complexes in order to facilitate the generation of

Indexed as

Antineoplastic AgentsPhotochemotherapyCell Line, TumorIridiumLigandsPhotosensitizing AgentsAntineoplastic AgentsIridiumLigandsPhotosensitizing Agents

Identifiers

PMID38291666
PMCPMC10859961
OpenAlexW4391401244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.