Evidence map›Paper›PMID 38291452›Full record

ReviewVirology journal2024

A state-of-the-art review of the recent advances in exosome isolation and detection methods in viral infection.

Amirsasan Gorgzadeh, Ahmad Nazari, Adnan Ali Ehsan Ismaeel, Diba Safarzadeh, Jawad A K Hassan, Saman Mohammadzadehsaliani, Hadis Kheradjoo, Pooneh Yasamineh, Saman Yasamineh

Open access · goldAbstract readReview
In one paragraph

Review in Virology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Current trends in exosomes as therapeutic drug delivery systems.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  9. Review
  10. Article
  11. The Role of Extracellular Vesicles in Epstein-Barr Virus Immunology and Pathogenesis for Possible Diagnostic and Therapeutic Direction.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Exosome-like Nanoparticles Extracted from Plant Cells for Diabetes Therapy.International journal of molecular sciences · 2025
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Amirsasan GorgzadehFaculty of Pharmacy, Jondi Shapour University, Ahvaz, Iran.
Ahmad NazariTehran University of Medical Sciences, Tehran, Iran.
Adnan Ali Ehsan IsmaeelDepartment of Pharmacy, Al-Noor University College, Mosul, Nineveh, Iraq.
Diba SafarzadehVocational School of Health Service, Near East University, Nicosia, Cyprus.
Jawad A K HassanNational University of Science and Technology, Nasiriyah, Dhi Qar, Iraq.
Saman MohammadzadehsalianiOphthalmology Department, Buraimi Hospital, Buraimi, Oman.
Hadis KheradjooLaboratory Department, Buraimi Hospital, Buraimi, Oman.
Pooneh YasaminehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Saman YasaminehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran. Yassaman124@gmail.com.
Islamic Azad University of Tabriz · IRAl-Nisour University College · IQNear East University · CYTehran University of Medical Sciences · IRThi Qar University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins, RNA, DNA, lipids, and carbohydrates are only some of the molecular components found in exosomes released by tumor cells. They play an essential role in healthy and diseased cells as messengers of short- and long-distance intercellular communication. However, since exosomes are released by every kind of cell and may be found in blood and other bodily fluids, they may one day serve as biomarkers for a wide range of disorders. In many pathological conditions, including cancer, inflammation, and infection, they play a role. It has been shown that the biogenesis of exosomes is analogous to that of viruses and that the exosomal cargo plays an essential role in the propagation, dissemination, and infection of several viruses. Bidirectional modulation of the immune response is achieved by the ability of exosomes associated with viruses to facilitate immunological escape and stimulate the body's antiviral immune response. Recently, exosomes have received a lot of interest due to their potential therapeutic use as biomarkers for viral infections such as human immunodeficiency virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), and SARS-CoV-2. This article discusses the purification procedures and detection techniques for exosomes and examines the research on exosomes as a biomarker of viral infection.

Indexed as

Epstein-Barr Virus InfectionsExosomesBiomarkersCell CommunicationHerpesvirus 4, HumanHumansBiomarkersBiomarkersDetectionExosomePurificationsViral infection

Identifiers

PMID38291452
PMCPMC10829349
OpenAlexW4391362396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.