Evidence map›Paper›PMID 38291400›Full record

ReviewMolecular cancer2024

Mapping cancer biology in space: applications and perspectives on spatial omics for oncology.

Sumin Lee, Gyeongjun Kim, JinYoung Lee, Amos C Lee, Sunghoon Kwon

Abstract readReview
In one paragraph

Review in Molecular cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Immunophenotyping by Spatial Biology.Methods in molecular biology (Clifton, N.J.) · 2027
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  11. Special Issue "Molecular Progression in Genome-Related Diseases".International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sumin Lee *Department of Electrical and Computer Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Gyeongjun Kim *Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, 08826, Republic of Korea.
JinYoung LeeDivision of Engineering Science, University of Toronto, Toronto, Ontario, ON, M5S 3H6, Canada.
Amos C Lee *Meteor Biotech,, Co. Ltd, Seoul, 08826, Republic of Korea. amoslee89@gmail.com.
Sunghoon Kwon *Department of Electrical and Computer Engineering, Seoul National University, Seoul, 08826, Republic of Korea. skwon@snu.ac.kr.

Funding

Ministry of Science and ICT, KR 2020R1A3B3079653Ministry of Science and ICT, KR RS-2023-00266110Ministry of Science, ICT and Future Planning, KR BK FOURMinistry of Trade, Industry and Energy, KR 20024391
6 · The paper itself

Abstract

Technologies to decipher cellular biology, such as bulk sequencing technologies and single-cell sequencing technologies, have greatly assisted novel findings in tumor biology. Recent findings in tumor biology suggest that tumors construct architectures that influence the underlying cancerous mechanisms. Increasing research has reported novel techniques to map the tissue in a spatial context or targeted sampling-based characterization and has introduced such technologies to solve oncology regarding tumor heterogeneity, tumor microenvironment, and spatially located biomarkers. In this study, we address spatial technologies that can delineate the omics profile in a spatial context, novel findings discovered via spatial technologies in oncology, and suggest perspectives regarding therapeutic approaches and further technological developments.

Indexed as

BiologyNeoplasmsHumansMedical OncologyTumor Microenvironment

Identifiers

PMID38291400
PMCPMC10826015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.