Evidence map›Paper›PMID 38291359›Full record

ArticleBMC infectious diseases2024

Factors associated with an unsuppressed viral load among HIV-positive individuals attending STI services in South Africa, 2019.

Marceline Mapiye, Khuliso Ravhuhali, Alex de Voux, Tendesayi Kufa

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marceline MapiyeFaculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa. marceydhliwayo@gmail.com.
Khuliso RavhuhaliSouth African Field Epidemiology Training ProgrammeProgramme, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.
Alex de VouxSouth African Field Epidemiology Training ProgrammeProgramme, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.
Tendesayi KufaFaculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
National Health Laboratory Service · ZAUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs), particularly in the absence of viral suppression, increase the risk of HIV transmission to uninfected partners. We determined factors associated with having an unsuppressed VL among HIV-positive individuals attending STI services in South Africa (SA).

methodsWe analysed secondary cross-sectional data collected on HIV-positive individuals presenting with STI symptoms s at sentinel sites in Western Cape and Gauteng provinces between January-December 2019 in SA. We compared demographic characteristics of individuals on ART or not on ART, and a Poisson regression model to identify factors associated with having an unsuppressed VL (≥ 50 copies/ml) was used.

resultsAmong 93 HIV-positive individuals attending STI services with VL data, the median age was 32 years (IQR 27-37). Thirty-two (34.41%) individuals were on ART compared to 61 (65.59%) not on ART. Most of those on ART (56.25%) had an unsuppressed VL, while 86.89% of those not on ART had an unsuppressed VL. ART use was associated with a 33% lower prevalence of having unsuppressed VL. In a model adjusting for age, age at first sex and oral sex, none of the factors were significant. Among those on ART, individuals < 25 years were more likely to have an unsuppressed VL (aPRR = 1.94: 95% CI = 1.27-2.97) compared to those ≥ 25 years.

conclusionART use among HIV-positive individuals was low and VL suppression among those on ART was sub-optimal. Intensified ART initiation and adherence support to HIV-positive individuals seeking STI services could improve VL suppression.

Indexed as

Anti-HIV AgentsHIV InfectionsSexually Transmitted DiseasesAdultAnti-Retroviral AgentsCross-Sectional StudiesHumansSouth AfricaViral LoadAnti-HIV AgentsAnti-Retroviral Agents95–95-95Antiretroviral therapyHIVSexually Transmitted InfectionsSouth AfricaVLVL suppression

Identifiers

PMID38291359
PMCPMC10829169
OpenAlexW4391349164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.