Evidence map›Paper›PMID 38291351›Full record

ArticleBMC cancer2024

Development and validation of a

Huiling Liu, Yongbin Cui, Cheng Chang, Zichun Zhou, Yalin Zhang, Changsheng Ma, Yong Yin, Ruozheng Wang

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Huiling Liu *Department of Radiation Oncology, The Third Affillated Teaching Hospital of Xinjiang Medical University, Affilated Cancer Hospital, Urumuqi, China.
Yongbin Cui *Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Cheng ChangDepartment of Nuclear Medicine, Third Affiliated Hospital of Xinjiang Medical University, State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Urumqi, China.
Zichun ZhouSchool of Mechanical, Electrical and Information Engineering, Shandong University, Weihai, China.
Yalin ZhangDepartment of Radiation Oncology, The Third Affillated Teaching Hospital of Xinjiang Medical University, Affilated Cancer Hospital, Urumuqi, China.
Changsheng MaDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Yong Yin *Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China. yinyongsd@126.com.
Ruozheng Wang *Department of Radiation Oncology, The Third Affillated Teaching Hospital of Xinjiang Medical University, Affilated Cancer Hospital, Urumuqi, China. wrz8526@vip.163.com.
Xinjiang Medical University · CNShandong First Medical University · CNShandong Tumor Hospital · CNShandong University · CNTumor Hospital of Xinjiang Medical University · CN

Funding

the Key Research and Development Program of Xinjiang Uygur Autonomous Region of China 2022B03019-5the Special Funds Project of Central Guidance on Local Science and Technology Development ZYYD2022B18the State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asian Fund SKL-HIDCA-2020-GJ4
6 · The paper itself

Abstract

backgroundThe existing staging system cannot meet the needs of accurate survival prediction. Accurate survival prediction for locally advanced cervical cancer (LACC) patients who have undergone concurrent radiochemotherapy (CCRT) can improve their treatment management. Thus, this present study aimed to develop and validate radiomics models based on pretreatment

methodsThe data from 190 consecutive patients with LACC who underwent pretreatment

resultsIn total, one clinical, one PET radiomics, and three CT radiomics features were significantly associated with progression-free survival in the training cohort. Across all three cohorts, the combined model displayed better efficacy and clinical utility than any of these parameters alone in predicting 3-year progression-free survival (area under curve: 0.661, 0.718, and 0.775; C-index: 0.698, 0.724, and 0.705, respectively) and 5-year progression-free survival (area under curve: 0.661, 0.711, and 0.767; C-index, 0.698, 0.722, and 0.676, respectively). On subsequent construction of a nomogram, the calibration curve demonstrated good agreement between actually observed and nomogram-predicted values.

conclusionsIn this study, a clinico-radiomics prediction model was developed and successfully validated using an independent external validation cohort. The nomogram incorporating radiomics and clinical features could be a useful clinical tool for the early and accurate assessment of long-term prognosis in patients with LACC patients who undergo concurrent chemoradiotherapy.

Indexed as

NomogramsUterine Cervical NeoplasmsFemaleFluorodeoxyglucose F18HumansPositron Emission Tomography Computed TomographyProgression-Free SurvivalRadiomicsRetrospective StudiesFluorodeoxyglucose F1818F-FDG PET/CTLocally advanced cervical cancerMachine learningPrediction modelProgression free survivalRadiomics

Identifiers

PMID38291351
PMCPMC10826285
OpenAlexW4391350843

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.