ArticleJournal of cancer survivorship : research and practice2025
A prospective evaluation of quality of life, psychosocial distress, and functional outcomes two years after radical cystectomy and urinary diversion in 842 German bladder cancer patients.
Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The impact of high-grade complications on quality of life and psychosocial distress in the early period after radical cystectomy.BJUI compass · 2026Article
- Psychosocial distress after radical prostatectomy, radical cystectomy, or (partial) nephrectomy - a comprehensive analysis of 4,290 German cancer patients during the COVID-19 pandemic.Journal of cancer survivorship : research and practice · 2026Article
- Impact of Surgical Wait Time on Survival After Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Retrospective Cohort Study.Cancer management and research · 2026Article
- Perioperative mental health needs in urological and genitourinary surgery: a scoping review.Frontiers in public health · 2026Article
- Application of transurethral blue laser vaporization of the prostate in patients aged 80 and above: a single-center clinical analysis of 157 cases.Lasers in medical science · 2025Article
- Review
- Article
- New Bladder Preservation Strategies in Urothelial Carcinoma of the Bladder.Deutsches Arzteblatt international · 2025Review
- Factors influencing fear of disease recurrence in postoperative craniopharyngioma patients.American journal of translational research · 2025Article
- Prospective comparative study of quality of life in patients with bladder cancer undergoing cystectomy with ileal conduit or bladder preservation.BMJ oncology · 2024Article
- Difficult conversations in bladder cancer survivorship: Integrating mental health and intimacy into routine urologic care.Bladder cancer (Amsterdam, Netherlands)Article
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Authors and funding
9 authors.
Funding
Abstract
purposeThis study aims to evaluate survival, health-related quality of life (HRQoL), psychosocial distress, and functional outcomes after radical cystectomy (RC) and urinary diversion for ileal neobladder (INB) or ileal conduit (IC) in a contemporary German cohort of bladder cancer patients.
methodsPatients undergoing inpatient rehabilitation after RC between April 2018 and December 2019 in one high-volume rehabilitation center were surveyed regarding HRQoL, psychosocial distress, and functional outcomes until two years after RC.
resultsEight-hundred forty-two patients (683 male, 159 female; 395 INB, 447 IC) were included. Patients with an IC suffered more often from locally advanced disease (≥ pT3; 41.4% vs. 24.1%, p < 0.001) and lymph node metastases (19.9% vs. 11.8%, p = 0.002), resulting in worse probability of survival (p < 0.001). Global HRQoL improved steadily during follow-up, but significant differences in subscales persisted between cohorts. Multivariable regression analysis identified IC, male sex, and patient age ≤ 59 years as independent predictors for persistent high psychosocial distress. Almost 42% of female patients reported severe urinary incontinence two years after RC. Most men reported severely diminished erectile function, even after nerve-sparing surgery.
conclusionGlobal HRQoL two years after RC is comparable to the general German population. Female patients should be informed about worse continence rates. Conversely, men should be educated about erectile dysfunction. Aftercare should include psycho-oncologic counseling, especially for patients at risk. IMPLICATIONS FOR CANCER SURVIVORS: Patients should be counseled on long-term functional outcomes and persistent psychosocial distress after RC. Closer cooperation between urologists and psycho-oncologists is needed.
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