Evidence map›Paper›PMID 38291214›Full record

ArticleJournal of cancer research and clinical oncology2024

The impact of divergent forms of social support on health-related quality of life in patients with multiple myeloma and its precursor states.

Anja Greinacher, Rea Kuehl, Elias K Mai, Hartmut Goldschmidt, Joachim Wiskemann, Anna Fleischer, Leo Rasche, Ulrike Dapunt, Imad Maatouk

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer research and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04328038 (Personalized Exercise Oncology), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04328038 active not recruitingnot on this map

Personalized Exercise Oncology (PEXO) - Study

TypeobservationalSponsorUniversity Hospital HeidelbergRan2018 to 2026Enrolled800ConditionsCancer, Health BehaviorArmsSurvey
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Patient preferences for treatment‑free intervals in multiple myeloma: mixed‑methods insights on monitoring trade‑offs and supportive care improvements.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anja GreinacherInstitute of Medical Psychology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8546-3335
Rea KuehlNational Center for Tumor Diseases, Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Elias K MaiDepartment of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6226-1252
Hartmut GoldschmidtDepartment of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0961-0035
Joachim WiskemannNational Center for Tumor Diseases, Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5971-5436
Anna FleischerDepartment of Internal Medicine II, Julius-Maximilian University Würzburg, Würzburg, Germany.ORCID http://orcid.org/0009-0009-8760-3931
Leo RascheDepartment of Internal Medicine II, Julius-Maximilian University Würzburg, Würzburg, Germany.ORCID http://orcid.org/0000-0002-9536-9649
Ulrike DapuntDepartment of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-7396-6074
Imad MaatoukDepartment of Internal Medicine II, Julius-Maximilian University Würzburg, Würzburg, Germany. Maatouk_I@ukw.de.ORCID http://orcid.org/0000-0002-8030-1182

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMultiple myeloma is a largely incurable disease. Patients suffer from the cancer, therapeutic side effects, and often psychological symptoms. Not only multiple myeloma patients but also patients with precursor diseases show high psychological distress. Today, treatment option evaluations are increasingly performed in combination with health-related quality of life (HRQoL) assessments. One factor that is positively associated with HRQoL is social support.

methodsOur recent study used questionnaires (EORTC QLQ-C30, EORTC QLQ-MY20, Illness-specific Social Support Scale) to investigate the influence of positive and negative aspects of social support on HRQoL in patients with multiple myeloma and its precursors.

resultsMultiple linear regression analyses with sex, age, treatment line, hemoglobin level, and number of comorbidities as control variables show that positive social support had a significant beneficial association with emotional function (β = 0.323) and social function (β = 0.251). Detrimental interactions had a significant negative association with social function (β =  - 0.209) and a significant positive association with side effects of treatment (β = 0.266).

conclusionTherefore, screening for social support and, if needed, psycho-oncological care can be an important resource and should be implemented in routine care. CLINICAL

trial registrationThis study was registered with clinicaltrials.gov (NCT04328038).

Indexed as

Multiple MyelomaQuality of LifeAnxietyHumansSocial SupportSurveys and QuestionnairesDetrimental interactionHealth-related quality of lifeMultiple myelomaPositive supportPsychological distressSocial support

Identifiers

PMID38291214
PMCPMC10827961

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.