ArticleCommunications biology2024
A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- The associations of human genetic variations with airway microbiome, environmental exposures, and respiratory health.mSystems · 2026Article
- Current status of intranasal and inhaled COVID-19 vaccines.NPJ vaccines · 2026Review
- Interplay of the nasal microbiome and epigenome among adolescents.Clinical epigenetics · 2026Article
- Genomics of host-microbiome interactions in humans.Nature reviews. Genetics · 2026Review
- Disease-modifying therapies are associated with improved olfactory function via NK cell- microbiota interactions in multiple sclerosis.Frontiers in immunology · 2026Article
- The Association of Allergic Rhinitis with Chronic Adenotonsillar Diseases and Chronic Rhinosinusitis: A Mendelian Randomization Study.Combinatorial chemistry & high throughput screening · 2026Article
- Host-specific bacterial modulation of airway gene expression and alternative splicing.mSphere · 2025Article
- Exploring the plausible genetic relationship of salivary and tongue microbiome with periodontitis: A mendelian randomization study.The Saudi dental journal · 2025Article
- Causal relationship between oral/gut microbiota and lung cancer: a two-sample Mendelian randomization study.Discover oncology · 2025Article
- Functionally enriched human polymorphisms associate to species in the chronic wound microbiome.NPJ biofilms and microbiomes · 2025Article
- Preliminary Insights Into the Relationship Between the Gut Microbiome and Host Genome in Posttraumatic Stress Disorder.Genes, brain, and behavior · 2025Article
- Review
- The host genotype actively shapes its microbiome across generations in laboratory mice.Microbiome · 2024Article
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.Microbiome · 2024Article
- Review
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. Here, by dissecting the human genome and nasal metagenome data from 1401 healthy individuals, we demonstrated that the top three host genetic principal components strongly correlated with the nasal microbiota diversity and composition. The genetic association analyses identified 63 genome-wide significant loci affecting the nasal microbial taxa and functions, of which 2 loci reached study-wide significance (p < 1.7 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.