Evidence map›Paper›PMID 38290851›Full record

ArticleeNeuro2024

Temporal Alterations in White Matter in An

Zachery D Morrissey, Jin Gao, Aashutosh Shetti, Wenping Li, Liang Zhan, Weiguo Li, Igor Fortel, Takaomi Saido, Takashi Saito, Olusola Ajilore and 3 more

Abstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Therapeutic modulation of neurogenesis to improve hippocampal plasticity and cognition in aging and Alzheimer's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zachery D MorrisseyGraduate Program in Neuroscience, University of Illinois Chicago, Chicago, Illinois 60612.ORCID https://orcid.org/0000-0002-8346-4876
Jin GaoDepartment of Electrical & Computer Engineering, University of Illinois Chicago, Chicago, Illinois 60607.
Aashutosh ShettiDepartment of Anatomy & Cell Biology, University of Illinois Chicago, Chicago, Illinois 60612.
Wenping LiDepartment of Chemistry, University of Illinois Chicago, Chicago, Illinois 60607.
Liang ZhanDepartment of Electrical & Computer Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Weiguo LiPreclinical Imaging Core, University of Illinois Chicago, Chicago, Illinois 60612.
Igor FortelDepartment of Bioengineering, University of Illinois Chicago, Chicago, Illinois 60607.
Takaomi SaidoLaboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Takashi SaitoDepartment of Neurocognitive Science, Institute of Brain Science, Nagoya City University, Nagoya 467-8601, Japan.
Olusola AjiloreDepartment of Psychiatry, University of Illinois Chicago, Chicago, Illinois 60612.ORCID https://orcid.org/0000-0003-0737-0437
Stephanie M ColognaDepartment of Chemistry, University of Illinois Chicago, Chicago, Illinois 60607.
Orly LazarovDepartment of Anatomy & Cell Biology, University of Illinois Chicago, Chicago, Illinois 60612 olazarov@uic.edu.ORCID https://orcid.org/0000-0002-5887-948X
Alex D LeowDepartment of Psychiatry, University of Illinois Chicago, Chicago, Illinois 60612.

Funding

The role of PS1 in regulation of adult neurogenesis in the intact and Alzheimer?sR01AG033570 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Orly Lazarov · 2009 to 2026
$5.6M
Training in the Neuroscience of Mental HealthT32MH067631 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RASENICK, MARK M. · 2004 to 2024
$4.8M
Hippocampal neurogenesis in cognitive function and dysfunction in Alzheimer's disease.R01AG076940 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Orly Lazarov · 2022 to 2026
$3.7M
Novel Therapeutic Approaches for NPC DiseaseR01NS124784 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Vinay Aakalu, Stephanie M Cologna · 2022 to 2026
$2.9M
Plasticity circuits in Alzheimer s diseaseRF1AG033570 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2020 to 2021
$2.9M
Mechanisms underlying sporadic Alzheimer's diseaseR01AG060238 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2018 to 2022
$2.4M
Training program in the biology and translational research on Alzheimer's diseaseand related dementiasT32AG057468 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Stephanie M Cologna, Orly Lazarov · 2017 to 2026
$2.3M
Acceleration of AD Phenotypes in Asymptomatic Mouse ModelsR01AG062251 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2018 to 2022
$2.2M
Development of autophagy modulators for evaluation as a therapeutic strategy for Niemann-Pick Type CR01NS114413 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI COLOGNA, STEPHANIE M · 2020 to 2024
$2.0M
Connecting late-life depression and cognition with statistical physics based connectomics and sparse Frechet regressionRF1MH125928 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEOW, ALEX, WU, YICHAO · 2021 to 2021
$1.3M
CRCNS: Investigating Brain Dynamics through the Lens of Statistical MechanicsR01AG071243 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEOW, ALEX, ZHAN, LIANG · 2020 to 2022
$882k
Highly-sensitive imaging markers for early detection of Alzheimer's Disease using multi-view connectomicsR21AG056782 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEOW, ALEX, THOMPSON, PAUL M · 2017 to 2018
$425k
NIA NIH HHS R01 AG033570NIA NIH HHS R01 AG060238NIA NIH HHS R01 AG062251NIA NIH HHS R01 AG071243NIA NIH HHS R01 AG076940NIA NIH HHS R21 AG056782NIA NIH HHS RF1 AG033570NIA NIH HHS T32 AG057468NIMH NIH HHS RF1 MH125928NIMH NIH HHS T32 MH067631NINDS NIH HHS R01 NS114413NINDS NIH HHS R01 NS124784
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common form of dementia and results in neurodegeneration and cognitive impairment. White matter (WM) is affected in AD and has implications for neural circuitry and cognitive function. The trajectory of these changes across age, however, is still not well understood, especially at earlier stages in life. To address this, we used the

Indexed as

Alzheimer DiseaseWhite MatterAmyloid beta-Protein PrecursorAnimalsBrainDiffusion Tensor ImagingDisease Models, AnimalHumansMiceAmyloid beta-Protein PrecursorAlzheimer's diseaseAppNL-G-F/NL-G-FDTImyelinoligodendrocyteswhite matter

Identifiers

PMID38290851
PMCPMC10897532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.