Evidence map›Paper›PMID 38289961›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation.

Gwonjin Lee, Brian J Sanderson, Thomas J Ellis, Brian P Dilkes, John K McKay, Jon Ågren, Christopher G Oakley

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Climate change and plant genomic plasticity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  12. Life-history trade-offs explain local adaptation inbioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Genetic basis and trade-offs of cold acclimation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Gwonjin LeeDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907.ORCID 0000-0003-2207-3975
Brian J SandersonDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907.ORCID 0000-0002-0310-0440
Thomas J EllisPlant Ecology and Evolution, Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University, Uppsala SE-752 36, Sweden.ORCID 0000-0002-8511-0254
Brian P DilkesCenter for Plant Biology, Purdue University, West Lafayette, IN 47907.ORCID 0000-0003-2799-954X
John K McKayDepartment of Soil and Crop Sciences, Colorado State University, Fort Collins, CO 80523.
Jon ÅgrenPlant Ecology and Evolution, Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University, Uppsala SE-752 36, Sweden.ORCID 0000-0001-9573-2463
Christopher G OakleyDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907.ORCID 0000-0002-8082-5621
Research Institute of Molecular Pathology · ATUniversity of Kansas · USUppsala University · SE

Funding

National Science Foundation (NSF) DEB-1743273National Science Foundation (NSF) IOS-2246545Vetenskapsrådet (VR) 2016-05435Vetenskapsrådet (VR) 2020-04434
6 · The paper itself

Abstract

Identifying the genetic basis of local adaptation and fitness trade-offs across environments is a central goal of evolutionary biology. Cold acclimation is an adaptive plastic response for surviving seasonal freezing, and costs of acclimation may be a general mechanism for fitness trade-offs across environments in temperate zone species. Starting with locally adapted ecotypes of

Indexed as

ArabidopsisArabidopsis ProteinsAcclimatizationCold TemperatureGenetic FitnessMutationTranscription FactorsArabidopsis ProteinsTranscription Factorsantagonistic pleiotropycold acclimationgenetic trade-offlocal adaptationplasticity

Identifiers

PMID38289961
PMCPMC10861903
OpenAlexW4391343194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.