Evidence map›Paper›PMID 38289418›Full record

ReviewEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2024

Mental health is strongly associated with capability after lower extremity injury treated with free flap limb salvage or amputation.

David D Krijgh, Teun Teunis, Emile B List, Marc A M Mureau, Antonius J M Luijsterburg, Wiesje Maarse, Pascal P A Schellekens, Falco Hietbrink, Tim de Jong, J Henk Coert

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Mental Health Risk Factors for Postoperative Pain in Head and Neck Free Flap Reconstruction Patients.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  3. Article
  4. Article
  5. Trends in Lower Limb Orthoplastic Surgery: A Bibliometric Analysis.Plastic and reconstructive surgery. Global open · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

David D KrijghDepartment of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Heidelberglaan 100, Postbus, 85500, Postcode 3508, GA, Utrecht, the Netherlands. d.d.krijgh@umcutrecht.nl.ORCID http://orcid.org/0000-0002-3461-2502
Teun TeunisDepartment of Plastic Surgery, University Pittsburgh Medical Center, Pittsburgh, USA.
Emile B ListDepartment of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Heidelberglaan 100, Postbus, 85500, Postcode 3508, GA, Utrecht, the Netherlands.
Marc A M MureauDepartment of Plastic and Reconstructive Surgery, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Antonius J M LuijsterburgDepartment of Plastic and Reconstructive Surgery, University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Wiesje MaarseDepartment of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Heidelberglaan 100, Postbus, 85500, Postcode 3508, GA, Utrecht, the Netherlands.
Pascal P A SchellekensDepartment of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Heidelberglaan 100, Postbus, 85500, Postcode 3508, GA, Utrecht, the Netherlands.
Falco HietbrinkDepartment of Trauma Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Tim de JongDepartment of Plastic, Reconstructive and Hand Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
J Henk CoertDepartment of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Heidelberglaan 100, Postbus, 85500, Postcode 3508, GA, Utrecht, the Netherlands.
Heidelberg University · DEErasmus MC · NLRadboud University Nijmegen · NLUniversity Medical Center Utrecht · NLUniversity of Pittsburgh Medical Center · USUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge about factors associated with long-term outcomes, after severe traumatic injury to the lower extremity, can aid with the difficult decision whether to salvage or amputate the leg and improve outcome. We therefore studied factors independently associated with capability at a minimum of 1 year after amputation or free flap limb salvage.

methodsWe included 135 subjects with a free flap lower extremity reconstruction and 41 subjects with amputation, between 1991 and 2021 at two urban-level 1 trauma centers with a mean follow-up of 11 ± 7 years. Long-term physical functioning was assessed using the Physical Component Score (PCS) of the Short-Form 36 (SF36) and the Lower Extremity Functional Scale (LEFS) questionnaires. Independent variables included demographics, injury characteristics, and the Mental Component Score (MCS) of the SF36.

resultsGreater mental health was independently and strongly associated with greater capability, independent of amputation or limb reconstruction. Mental health explained 33% of the variation in PCS and 57% of the variation in LEFS. Injury location at the knee or leg was associated with greater capability, compared to the foot or ankle. Amputation or limb reconstruction was not associated with capability. DISCUSSION: This study adds to the growing body of knowledge that physical health is best regarded through the lens of the bio-psycho-social model in which mental health is a strong determinant. This study supports making mental health an important aspect of rehabilitation after major lower extremity injury, regardless of amputation or limb salvage.

Indexed as

Amputation, SurgicalFree Tissue FlapsLeg InjuriesLimb SalvageMental HealthAdultFemaleHumansMaleMiddle AgedPlastic Surgery ProceduresRetrospective StudiesAmputationFree flapLower legQuality of lifeReconstruction

Identifiers

PMID38289418
PMCPMC11249639
OpenAlexW4391354668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.