Evidence map›Paper›PMID 38289204›Full record

Observational studyJBRA assisted reproduction2024

Progesterone levels on hCG day and oocyte maturation in a Mexican IVF program.

Alfredo Cortés-Vazquez, Denisse Veliz-Figueroa, Karla Vargas-Estrada, Jesús-Daniel Moreno-García, Alfredo Cortés-Algara

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in JBRA assisted reproduction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alfredo Cortés-VazquezReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Denisse Veliz-FigueroaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Karla Vargas-EstradaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Jesús-Daniel Moreno-GarcíaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Alfredo Cortés-AlgaraReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDoes progesterone levels on hCG day influence maturation rates and number of mature oocytes during ovarian stimulation for IVF/ICSI cycles?.

methodsA retrospective, observational, analytic, cross-sectional and cohort study was performed at the Reproductive Endocrinology Department of the Centro Médico Nacional 20 de Noviembre in Mexico City between 2015 to 2020. All female patients underwent an ovarian stimulation cycle for IVF/ICSI, either with a mild or conventional stimulation protocol. Patients were classified according to their progesterone levels, Group 1 <1.5ng/ml and Group 2 >1.5mg/ml. A Spearman Rho test, a simple linear regression model, a Principal Component Analysis and a Student's T-test, were performed.

resultsA total of 600 patients were included. The overall results showed that there is a positive correlation between the number of retrieved, mature oocytes and progesterone levels on HCG day. After the Principal Component Analysis we observed that poor ovarian responders had the lowest maturation rate and number of mature oocytes. While the Student's t test showed that progesterone levels beyond 1.5ng/ml are associated to a higher number of mature oocytes but not a better maturation rate.

conclusionsHigher serum progesterone levels are associated with increased retrieved and mature oocytes in high responders. At the same time, higher progesterone levels in lower responders are not associated with optimal ovarian response.

Indexed as

Chorionic GonadotropinFertilization in VitroOocytesOvulation InductionProgesteroneAdultCohort StudiesCross-Sectional StudiesFemaleHumansMexicoPregnancyRetrospective StudiesChorionic GonadotropinProgesteronecompetencematurationoocyteprogesterone

Identifiers

PMID38289204
PMCPMC11152430
OpenAlexW4391364833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.