Evidence map›Paper›PMID 38289141›Full record

ArticlemBio2024

Exogenous butyrate inhibits butyrogenic metabolism and alters virulence phenotypes in

Daniel A Pensinger, Horia A Dobrila, David M Stevenson, Nicole D Hryckowian, Daniel Amador-Noguez, Andrew J Hryckowian

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. [Butyrate alleviatesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  3. Article
  4. EndD mediates butyrate-dependent toxin release inbioRxiv : the preprint server for biology · 2026
    Article
  5. Acidification-dependent suppression ofInfection and immunity · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Acidification-dependent suppression ofbioRxiv : the preprint server for biology · 2026
    Article
  10. The critical role ofApplied and environmental microbiology · 2026
    Article
  11. Article
  12. Gut microbes · 2025
    Article
  13. The emerging view on the roles of butyrate inInfection and immunity · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Impacts ofJournal of bacteriology · 2025
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Daniel A PensingerDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-6742-5527
Horia A DobrilaDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
David M StevensonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nicole D HryckowianDepartment of Medical Microbiology & Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Daniel Amador-NoguezDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-3568-3070
Andrew J HryckowianDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-8956-6259
University of Wisconsin–Madison · US

Funding

Mechanistic analysis of Toxoplasma gondii sexual development in tissue culture and mouse modelsF32AI172084 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIS, NICOLE MARIE · 2022 to 2024
$214k
NIAID NIH HHS F32 AI172084
6 · The paper itself

Abstract

The gut microbiome engenders colonization resistance against the diarrheal pathogen

Indexed as

Clostridioides difficileClostridium InfectionsAnimalsButyratesClostridioidesDiarrheaHumansMiceVirulenceButyratesenteric pathogensgram-positive bacteriametabolismpathogenesis

Identifiers

PMID38289141
PMCPMC10936429
OpenAlexW4391349190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.