Evidence map›Paper›PMID 38289124›Full record

ArticleInfection and immunity2024

Transmission-reducing and -enhancing monoclonal antibodies against

Geetha P Bansal, Maisa da Silva Araujo, Yi Cao, Emily Shaffer, Jessica Evangelista Araujo, Jansen Fernandes Medeiros, Clifford Hayashi, Joseph Vinetz, Nirbhay Kumar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Geetha P BansalDepartment of Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.ORCID 0000-0003-2204-0225
Maisa da Silva AraujoPlataforma de Produção e Infecção de Vetores da Malária, Laboratório de Entomologia - Fiocruz Rondônia, Porto Velho, Rondônia, Brazil.
Yi CaoDepartment of Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Emily ShafferDepartment of Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Jessica Evangelista AraujoPlataforma de Produção e Infecção de Vetores da Malária, Laboratório de Entomologia - Fiocruz Rondônia, Porto Velho, Rondônia, Brazil.
Jansen Fernandes MedeirosPlataforma de Produção e Infecção de Vetores da Malária, Laboratório de Entomologia - Fiocruz Rondônia, Porto Velho, Rondônia, Brazil.
Clifford HayashiDepartment of Global Health, George Washington University, Washington, DC, USA.
Joseph VinetzYale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-8344-2004
Nirbhay KumarDepartment of Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.ORCID 0000-0002-0358-4924
Tulane University · USUniversidade Federal de Rondônia · BRGeorge Washington University · USYale University · US

Funding

Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI CASTRO, MARCIA C. · 2010 to 2023
$20.1M
A DNA VACCINE TO PREVENT TRANSMISSION OF HUMAN MALARIAR01AI047089 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KUMAR, NIRBHAY · 2000 to 2011
$3.6M
Combination Vaccines to Interrupt Malaria TransmissionR01AI127544 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KUMAR, NIRBHAY · 2017 to 2020
$2.2M
Identification of Transmission blocking epitopes on P. vivax 48/45 proteinR03AI111138 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KUMAR, NIRBHAY · 2015 to 2016
$151k
NIAID NIH HHS R01 AI047089NIAID NIH HHS R01 AI127544NIAID NIH HHS R03 AI111138NIAID NIH HHS U19 AI089681
6 · The paper itself

Abstract

Gamete surface protein P48/45 has been shown to be important for male gamete fertility and a strong candidate for the development of a malaria transmission-blocking vaccine (TBV). However, TBV development for

Indexed as

Malaria VaccinesMalaria, VivaxAnimalsAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanEpitopesGerm CellsHumansMaleMembrane ProteinsPlasmodium vivaxAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanEpitopesMalaria VaccinesMembrane ProteinsAnopheles darlingimonoclonal antibodiesPlasmodium vivaxPvs48/45transmission-blocking vaccinetransmission-enhancing activitytransmission-reducing activity

Identifiers

PMID38289124
PMCPMC10929423
OpenAlexW4391361105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.