Evidence map›Paper›PMID 38289122›Full record

ArticleInfection and immunity2024

Layering vaccination with antibiotic therapy results in protection and clearance of

Kay B Barnes, Paul Brett, Mary Burtnick, Andreas Vente, Christine Bentley, Mark I Richards, Helen C Flick-Smith, Gary Burgess, Joanne E Thwaite, Thomas R Laws and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 4 countries.

Kay B BarnesDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.ORCID 0009-0002-3125-9413
Paul BrettUniversity of Nevada, Reno School of Medicine, Reno, Nevada, USA.
Mary BurtnickUniversity of Nevada, Reno School of Medicine, Reno, Nevada, USA.ORCID 0000-0001-6763-4348
Andreas VenteMerLion Pharmaceuticals, Berlin, Germany.
Christine BentleyMerLion Pharmaceuticals, Berlin, Germany.
Mark I RichardsDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Helen C Flick-SmithDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Gary BurgessDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Joanne E ThwaiteDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Thomas R LawsDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Thomas C MaishmanDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.
Michelle NelsonDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.ORCID 0000-0002-5983-7206
Sarah V HardingDefence Science and Technology Laboratory, Porton Down, Salisbury, United Kingdom.ORCID 0000-0003-0159-5117
Defence Science and Technology Laboratory · GBMerLion Pharma (Germany) · DEUniversity of Nevada, Reno · US

Funding

DOD | Defense Threat Reduction Agency (DTRA) HDTRA-12-D-0003_0019
6 · The paper itself

Abstract

Melioidosis is a disease that is difficult to treat due to the causative organism,

Indexed as

Burkholderia pseudomalleiMelioidosisAnimalsAnti-Bacterial AgentsDisease Models, AnimalMiceMice, Inbred BALB CVaccinationVaccines, SubunitAnti-Bacterial AgentsVaccines, SubunitBalb/cBurkholderia pseudomalleifinafloxacinlayered defencemelioidosissubunit vaccine

Identifiers

PMID38289122
PMCPMC10929409
OpenAlexW4391348993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.