Evidence map›Paper›PMID 38289119›Full record

ArticleJournal of virology2024

MicroRNA-22-3p displaces critical host factors from the 5' UTR and inhibits the translation of Coxsackievirus B3 RNA.

Priya Rani, Biju George, Sabarishree V, Somarghya Biswas, Madhurya V, Apala Pal, Raju S Rajmani, Saumitra Das

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Priya RaniDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.ORCID 0009-0000-9457-5638
Biju GeorgeDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Sabarishree VDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Somarghya BiswasDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Madhurya VDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Apala PalDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Raju S RajmaniMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Saumitra DasDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.ORCID 0000-0002-0640-3586
Indian Institute of Science Bangalore · INNational Institute of Biomedical Genomics · IN

Funding

Department of Biotechnology, Ministry of Science and Technology, India (DBT)DST | Science and Engineering Research Board (SERB)Ministry of Education, India (MoE)University Grants Commission (UGC)
6 · The paper itself

Abstract

Coxsackievirus B3 (CVB3) is known to cause acute myocarditis and pancreatitis in humans. We investigated the microRNAs (miRNAs) that can potentially govern the viral life cycle by binding to the untranslated regions (UTRs) of CVB3 RNA. MicroRNA-22-3p was short-listed, as its potential binding site overlapped with the region crucial for recruiting internal ribosome entry site

Indexed as

5' Untranslated RegionsCoxsackievirus InfectionsEnterovirus B, HumanHost Microbial InteractionsMicroRNAsProtein BiosynthesisRNA, ViralAnimalsAntiviral AgentsCysteine EndopeptidasesHeLa CellsHumansIntestine, SmallMiceMyocarditisProtocadherins5' Untranslated RegionsAntiviral AgentsCysteine EndopeptidasesMicroRNAsMIRN22 microRNA, humanMirn22 microRNA, mousePCDH1 protein, humanPcdh1 protein, mousepicornain 2A, PicornavirusProtocadherinsRNA, ViralViral ProteinsCoxsackievirus B3IRES-mediated translationmicroRNAs

Identifiers

PMID38289119
PMCPMC10883805
OpenAlexW4391348971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.