Evidence map›Paper›PMID 38289109›Full record

ArticleInfection and immunity2024

Oral streptococci

Sangeetha Senthil Kumar, Venugopal Gunda, Dakota M Reinartz, Kelvin W Pond, Curtis A Thorne, Paul Victor Santiago Raj, Michael D L Johnson, Justin E Wilson

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Journal for immunotherapy of cancer · 2026
    Article
  2. Metabolic Reprogramming of Macrophages Plays a Dual Role in Periodontitis: From Pathogenesis to Therapy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  3. Microbiota in cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  4. The emerging role of non-Gastroenterology report · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Streptococcus anginosus: the potential role in the progression of gastric cancer.Journal of cancer research and clinical oncology · 2025
    Review
  10. Frontiers in cellular and infection microbiology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sangeetha Senthil KumarDepartment of Immunobiology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-1004-0773
Venugopal GundaDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia, USA.
Dakota M ReinartzDepartment of Immunobiology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.
Kelvin W PondThe University of Arizona Cancer Center, Tucson, Arizona, USA.
Curtis A ThorneThe University of Arizona Cancer Center, Tucson, Arizona, USA.
Paul Victor Santiago RajR. Ken Coit College of Pharmacy, The University of Arizona, Tucson, Arizona, USA.
Michael D L JohnsonDepartment of Immunobiology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-6347-0208
Justin E WilsonDepartment of Immunobiology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-2803-3280
University of Arizona · USUniversity of Virginia · US

Funding

Integrative Cancer Scholars Training GrantT32CA009213 · NCI · UNIVERSITY OF ARIZONA · PI CAREW, JENNIFER S, CURIEL-LEWANDROWSKI, CLARA · 1985 to 2024
$8.6M
Elucidating the Orchestrated Bacterial Response to Copper ToxicityR35GM128653 · NIGMS · UNIVERSITY OF ARIZONA · PI Michael David Leslie Johnson · 2018 to 2026
$4.0M
Defining signaling networks in epithelial homeostasisR35GM147128 · NIGMS · UNIVERSITY OF ARIZONA · PI Curtis Andrew Thorne · 2022 to 2026
$2.0M
Regulation of Colon Cancer by AIM2K22CA212030 · NCI · UNIVERSITY OF ARIZONA · PI WILSON, JUSTIN ETHAN · 2018 to 2020
$479k
Contribution of Innate Immune Sensing on Head and Neck Squamous Cell Carcinoma (HNSCC)F31DE032263 · NIDCR · UNIVERSITY OF ARIZONA · PI REINARTZ, DAKOTA MICHAEL · 2022 to 2023
$81k
NCI NIH HHS K22 CA212030NCI NIH HHS T32 CA009213NIDCR NIH HHS F31 DE032263NIGMS NIH HHS R35 GM128653NIGMS NIH HHS R35 GM147128
6 · The paper itself

Abstract

Oral streptococci, key players in oral biofilm formation, are implicated in oral dysbiosis and various clinical conditions, including dental caries, gingivitis, periodontal disease, and oral cancer. Specifically,

Indexed as

Carcinoma, Squamous CellDental CariesMouth NeoplasmsSuccinatesHumansMacrophagesStreptococcusStreptococcus anginosusitaconic acidSuccinatesimmunometabolisminflammationmacrophagesoral streptococciS. anginosusS. mitis

Identifiers

PMID38289109
PMCPMC10929413
OpenAlexW4391361406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.