Evidence map›Paper›PMID 38288840›Full record

ArticleCurrent neurovascular research2024

Bacterial Pneumonia and Stroke Risk: A Nationwide Longitudinal Followup Study.

Joyce En-Hua Wang, Shih-Jen Tsai, Yen-Po Wang, Tzeng-Ji Chen, Tso-Jen Wang, Mu-Hong Chen

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Article in Current neurovascular research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Joyce En-Hua WangDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.
Shih-Jen TsaiDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.
Yen-Po WangInstitute of Brain Science, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tzeng-Ji ChenDepartment of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Tso-Jen WangTaoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan, 33058, Taiwan.
Mu-Hong ChenDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.
National Yang Ming Chiao Tung University · TWGeorgetown University · USMinistry of Health and Welfare · TW

Funding

Ministry of Science and Technology, Taiwan MOST110-2314-B-075-026, MOST110-2314-B-075-024 -MY3, MOST 109-2314-B-010-050-MY3, MOST111-2314-B-075 -014 -MY2, MOST 111-2314-B-075 -013, NSTC111-2314-B-A49-089-MY2Taipei, Taichung, Kaohsiung Veterans General Hospital, Tri-Service General Hospital, Academia Sinica Joint Research Program VTA112-V1-6-1, VTA113-V1-5-1Taipei Veterans General Hospital V111C-010, V111C-040, V111C-029, V112C-033, V113C-010, V113C-011, V113C-039Veterans General Hospitals and University System of Taiwan Joint Research Program VGHUST112-G1-8-1, VGHUST113-G1-8-1Yen Tjing Ling Medical Foundation CI-109-21, CI-109-22, CI-110-30, CI-113-30, CI-113-31, CI-113-32
6 · The paper itself

Abstract

backgroundPneumonia causes significant morbidity and mortality and has been associated with cardiovascular complications. Our study aimed to investigate the incidence of ischemic and hemorrhagic strokes following bacterial pneumonia.

methodsBetween 1997 and 2012, 10,931 subjects with bacterial pneumonia and 109,310 controls were enrolled from the Taiwan National Health Insurance Research Database, and were followed up to the end of 2013. The risk of stroke was estimated in Cox regression analyses with hazard ratios (HRs) and 95% confidence intervals (CIs).

resultsWhen compared to the control group, subjects in the bacterial pneumonia group had a higher incidence of developing ischemic stroke (2.7% versus 0.4%, p <0.001) and hemorrhagic stroke (0.7% versus 0.1%, p <0.001). The risk of stroke increases with repeated hospitalizations due to bacterial pneumonia. Across bacterial etiologies, bacterial pneumonia was a significant risk factor among 775 subjects who developed ischemic stroke (HR, 5.72; 95% CI, 4.92-6.65) and 193 subjects who developed hemorrhagic stroke (HR, 5.33; 95% CI, 3.91-7.26).

conclusionThe risks of developing ischemic stroke and hemorrhagic stroke are significant following bacterial pneumonia infection. The risk factors, clinical outcomes, and the disease course should also be profiled to better inform the monitoring of stroke development and the clinical management of bacterial pneumonia patients.

Indexed as

Pneumonia, BacterialStrokeAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansIncidenceLongitudinal StudiesMaleMiddle AgedRisk FactorsTaiwanYoung AdultBacterial pneumoniacardiovascular complicationsclinical managementcohort studyinfectious etiology.stroke

Identifiers

PMID38288840
OpenAlexW4391310686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.