Evidence map›Paper›PMID 38288598›Full record

ReviewCirculation. Genomic and precision medicine2024

Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems.

Zachery R Gregorich, Yanghai Zhang, Timothy J Kamp, Henk L Granzier, Wei Guo

Open access · greenAbstract readReview
In one paragraph

Review in Circulation. Genomic and precision medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Novel Truncating Variant c.1222DupC inCirculation. Genomic and precision medicine · 2026
    Article
  3. Review
  4. RBM20 variants disrupt CaSignal transduction and targeted therapy · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Early Onset Heart Failure due toClinical case reports · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Analysis ofCirculation. Genomic and precision medicine · 2025
    Article
  17. Article
  18. Methylations in dilated cardiomyopathy and heart failure.Frontiers in cardiovascular medicine · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachery R GregorichDepartment of Animal and Dairy Sciences (Z.R.G., Y.Z., W.G.), University of Wisconsin-Madison.
Yanghai ZhangDepartment of Animal and Dairy Sciences (Z.R.G., Y.Z., W.G.), University of Wisconsin-Madison.ORCID 0009-0003-5307-6148
Timothy J KampCellular and Molecular Arrhythmia Research Program (T.J.K.), University of Wisconsin-Madison.ORCID 0000-0003-2103-7876
Henk L GranzierDepartment of Cellular and Molecular Medicine, The University of Arizona, Tucson (H.L.G.).ORCID 0000-0002-9516-407X
Wei GuoDepartment of Animal and Dairy Sciences (Z.R.G., Y.Z., W.G.), University of Wisconsin-Madison.ORCID 0000-0002-9158-8107
University of Wisconsin–Madison · USUniversity of Arizona · US

Funding

Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7M
Role of the giant protein titin in cardiac health and diseaseR35HL144998 · NHLBI · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L. · 2019 to 2025
$6.3M
Posttranscriptional Regulation of RNA Binding Proteins in Heart FailureR01HL148733 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GUO, WEI · 2020 to 2023
$1.5M
Committed Cardiac Progenitors to Remuscularize the Failing Ischemic HeartU01HL148690 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI KAMP, TIMOTHY J., RAVAL, AMISH NARESH · 2019 to 2020
$761k
NHLBI NIH HHS R01 HL148733NHLBI NIH HHS R35 HL144998NHLBI NIH HHS U01 HL134764NHLBI NIH HHS U01 HL148690
6 · The paper itself

Abstract

RBM20 (RNA-binding motif protein 20) is a vertebrate- and muscle-specific RNA-binding protein that belongs to the serine-arginine-rich family of splicing factors. The

Indexed as

CardiomyopathiesCardiomyopathy, DilatedAnimalsArginineHumansMiceMyocytes, CardiacRNA-Binding ProteinsSerineArginineRBM20 protein, mouseRNA-Binding ProteinsSerinealternative splicingbiomolecular condensatescardiomyopathy, dilatedheart failureinduced pluripotent stem cell

Identifiers

PMID38288598
PMCPMC10923161
OpenAlexW4391360293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.