Evidence map›Paper›PMID 38288444›Full record

ArticleSynthetic and systems biotechnology2024

Efficient biosynthesis of creatine by whole-cell catalysis from guanidinoacetic acid in

Chunjian Li, Pengdong Sun, Guoqing Wei, Yuqi Zhu, Jingyuan Li, Yanfeng Liu, Jian Chen, Yang Deng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chunjian LiCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Pengdong SunCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Guoqing WeiCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Yuqi ZhuCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Jingyuan LiCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Yanfeng LiuQingdao Special Food Research Institute, Qingdao 266109, China.
Jian ChenQingdao Special Food Research Institute, Qingdao 266109, China.
Yang DengCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Qingdao Agricultural University · CNJiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creatine is a naturally occurring derivative of an amino acid commonly utilized in functional foods and pharmaceuticals. Nevertheless, the current industrial synthesis of creatine relies on chemical processes, which may hinder its utilization in certain applications. Therefore, a biological approach was devised that employs whole-cell biocatalysis in the bacterium

Indexed as

Corynebacterium glutamicumCreatineFood additiveGuanidinoacetate N-MethyltransferaseWhole-cell biocatalysis

Identifiers

PMID38288444
PMCPMC10823089
OpenAlexW4391492402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.