Evidence map›Paper›PMID 38288322›Full record

ArticleCureus2024

Enhancing Meniscal Repair: Investigating the Impact of an Exogenous Fibrin Clot.

Chrysanthos Chrysanthou, Nikolaos Laliotis, George K Paraskevas, Nikolaos Anastasopoulos, Gregory Packer

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06541756 (Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears - A Prospectively Randomized Controlled Trial), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06541756 narecruitingnot on this map

Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears - A Prospectively Randomized Controlled Trial

TypeinterventionalSponsorAnkara City Hospital BilkentRan2024 to 2029Enrolled120ConditionsMeniscus Tear, Meniscus Lesion, Fibrin Blood Clot, Knee InjuriesArmsFibrine Clot-augmented Meniscal Repair, Conventional Meniscal Repair
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Chrysanthos ChrysanthouOrthopaedics and Traumatology, Interbalkan Medical Center, Thessaloniki, GRC.
Nikolaos LaliotisOrthopaedics, Interbalkan Medical Center, Thessaloniki, GRC.
George K ParaskevasOrthopaedics, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Nikolaos AnastasopoulosAnatomy and Surgical Anatomy, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Gregory PackerOrthopaedics and Trauma, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.
Interbalkan Medical Center · GRAristotle University of Thessaloniki · GRTorbay and South Devon NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study conducted a comparative analysis of meniscal rupture repair, evaluating outcomes with and without the application of an exogenous fibrin clot to enhance meniscus repair. The research incorporated a relatively large sample size (24 patients) and employed a randomized control group with similar age characteristics and morphological types of meniscal ruptures as the study group. Notably, two postoperative follow-up times, at the third and 12th postoperative months, were utilized, distinguishing this study from related research. In the third postoperative month assessment, the fibrin clot technique demonstrated a significant advantage over simple stapling, as evidenced by markedly improved Tegner Lysholm Knee Scoring Scale (TLKSS) and Modified Cincinnati Rating System Questionnaire (MCRSQ) clinical assessment scores. Subsequent MRI scans at 12 months post-treatment revealed a high rate (91.67%) of complete healing in menisci treated with a fibrin clot, with only 4.17% exhibiting incomplete healing. This study expanded on previous research by including longitudinal ruptures and bucket-handle ruptures in addition to radial ruptures. The findings highlight a notable early improvement (third postoperative month) in the clinical assessment of longitudinal and bucket-handle ruptures treated with a fibrin clot during meniscus repair. This research contributes valuable insights into the efficacy of fibrin clots in enhancing meniscus repair, suggesting positive clinical and radiological outcomes, especially in the early stages postoperatively.

Indexed as

exogenous fibrin clot preparationfibrin clotfibrin clot augmentationmeniscal repair techniquesmeniscal repair with exogenous fibrin clot augmentation

Identifiers

PMID38288322
PMCPMC10824365
OpenAlexW4391293703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.