ArticleCureus2023
Prevalence of Dental and Skeletal Fluorosis Among School Children in Rural Areas of YSR Kadapa District, Andhra Pradesh, India.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Dental Morbidity Among School-Going Adolescents in a Fluoride-Endemic Belt of Rural Andhra Pradesh.Cureus · 2026Article
- Rosa roxburghii Tratt Juice Inhibits Fluoride Exposure-Induced Bone Damage in Male Rats by Regulating the Homeostasis of the ROS/TNF-α/NF-κB Pathway.Biological trace element research · 2026Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background Andhra Pradesh (AP) is one of the states in India found to have districts with endemic fluoride and YSR Kadapa district is one among them. Fluorosis is a well-known endemic disease affecting the hard tissues of the human body like teeth and bone and soft tissues like the kidneys, gastrointestinal system, nervous system, etc. Dental fluorosis is being proven as a biomarker for exposure to fluoride. This study evaluated the toxicity of fluoride in drinking water on the teeth (dental fluorosis) and on the bones (skeletal fluorosis) in YSR Kadapa district, AP. Material and methods A cross-sectional study was done in schools in the study areas and a total of 488 school children aged between eight to 14 years were screened for fluorosis. Consent from parents or legal representatives was taken. The information regarding personal details, source of drinking water, diet, and socio-demographic characteristics was obtained from children through a questionnaire. Oral examination of teeth was done to assess dental fluorosis by the Deans's fluorosis index and a general physical examination to assess skeletal fluorosis as per guidelines given by the Central Government of India in the National Program for Prevention of Fluorosis in India. Fluoride in drinking water samples and urine samples of school children was assessed by a fluoride ion meter. Statistical analysis was done using IBM SPSS Statistics for Windows, Version 25, (Released 2017; IBM Corp., Armonk, New York, United States). Descriptive statistics were used to assess the percentage distribution and Chi-square test of Independence for comparison between variables. Results The mean fluoride levels in water in the study areas ranged between 1.5mg/l to 4.2mg/l and there was a prevalence of 44.05% dental fluorosis and 0% skeletal fluorosis in the school children. A total of 48.47% of girls and 40.64% of boys were affected with dental fluorosis. A prevalence of 23.06% mild, 22.1% moderate, 5.31% very mild, and 4.55% severe dental fluorosis was observed in the examined children. Conclusion Our study results showed the presence of dental fluorosis with no clinical evidence of skeletal fluorosis among school children in the YSR Kadapa district of Andhra Pradesh. This indicates the fluoride toxicity on teeth in children confirming the exposure to fluoride in the YSR Kadapa district. So, further long-term follow-up surveys are necessary to evaluate skeletal fluorosis in these children though there was no clinical skeletal fluorosis. This highlights that measures need to be enforced by the local governance for the supply of defluorinated water in these areas.
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