Evidence map›Paper›PMID 38288134›Full record

ArticlePain reports2024

Empowered Relief, cognitive behavioral therapy, and health education for people with chronic pain: a comparison of outcomes at 6-month Follow-up for a randomized controlled trial.

Beth D Darnall, John W Burns, Juliette Hong, Anuradha Roy, Kristin Slater, Heather Poupore-King, Maisa S Ziadni, Dokyoung S You, Corinne Jung, Karon F Cook and 3 more

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pain reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06533345 (MERCI Chronic Pain Research Clinic), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06533345 narecruitingnot on this map

MERCI Chronic Pain Research Clinic (Medical Education and Research in Compassionate Integration/Intervention)

TypeinterventionalSponsorEdward Via Virginia College of Osteopathic MedicineRan2024 to 2027Enrolled120ConditionsChronic PainArmsBehavior Change Coaching, Nutrition, Autonomic Recalibration, Dry Needling, Osteopathic Manipulative Treatment
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Psychosocial Interventions for Chronic Non-Cancer Pain Among Older Adults: A Scoping Review.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Beth D DarnallDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
John W BurnsDepartment of Psychiatry and Behavioral Science, Rush University Medical Center, Chicago, IL, USA.
Juliette HongDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Anuradha RoyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Kristin SlaterDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Heather Poupore-KingDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Maisa S ZiadniDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Dokyoung S YouDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Corinne JungDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Karon F CookFeral Scholars, Broaddus, TX, USA.
Kate LorigDepartment of Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA.
Lu TianDepartment of Biomedical Data Science and (by courtesy) Statistics, Stanford University School of Medicine, Palo Alto, CA, USA.
Sean C MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Stanford University · USAlderson Broaddus University · USRush University Medical Center · US

Funding

Single Session Pain Catastrophizing Treatment: Comparative Efficacy & MechanismsR01AT008561 · NCCIH · STANFORD UNIVERSITY · PI DARNALL, BETH DENISE, MACKEY, SEAN C · 2015 to 2019
$3.9M
Research and Mentoring in Innovative Patient Oriented Pain and Opioid ScienceK24DA053564 · NIDA · STANFORD UNIVERSITY · PI Beth Denise Darnall · 2021 to 2026
$1.0M
Single Session Pain Catastrophizing Class: Efficacy & Mechanisms for Reducing Opioid Use Among Chronic Pain PatientsK23DA047473 · NIDA · STANFORD UNIVERSITY · PI ZIADNI, MAISA · 2019 to 2023
$796k
Mentoring in Discovery and Validation of Clinical Chronic Pain BiomarkersK24NS126781 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2021 to 2021
$324k
NCCIH NIH HHS R01 AT008561NIDA NIH HHS K23 DA047473NIDA NIH HHS K24 DA053564NINDS NIH HHS K24 NS126781
6 · The paper itself

Abstract

Introduction: We previously conducted a 3-arm randomized trial (263 adults with chronic low back pain) which compared group-based (1) single-session pain relief skills intervention (Empowered Relief; ER); (2) 8-session cognitive behavioral therapy (CBT) for chronic back pain; and (3) single-session health and back pain education class (HE). Results suggested non-inferiority of ER vs. CBT at 3 months post-treatment on an array of outcomes. Methods: Here, we tested the durability of treatment effects at 6 months post-treatment. We examined group differences in primary and secondary outcomes at 6 months and the degree to which outcomes eroded or improved from 3-month to 6-month within each treatment group. Results: Empowered Relief remained non-inferior to CBT on most outcomes, whereas both ER and CBT remained superior to HE on most outcomes. Outcome improvements within ER did not decrease significantly from 3-month to 6-month, and indeed ER showed additional 3- to 6-month improvements on pain catastrophizing, pain bothersomeness, and anxiety. Effects of ER at 6 months post-treatment (moderate term outcomes) kept pace with effects reported by participants who underwent 8-session CBT. Conclusions: The maintenance of these absolute levels implies strong stability of ER effects. Results extend to 6 months post-treatment previous findings documenting that ER and CBT exhibit similarly potent effects on outcomes.

Indexed as

BehavioralBriefCBTChronic low back painInterventionTreatment

Identifiers

PMID38288134
PMCPMC10824382
OpenAlexW4391161410

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.