Evidence map›Paper›PMID 38288115›Full record

ArticleFrontiers in immunology2023

Mitochondrial dynamics and metabolic regulation control T cell fate in the thymus.

Rima Elhage, Mairead Kelly, Nicolas Goudin, Jérôme Megret, Agnès Legrand, Ivan Nemazanyy, Cécilia Patitucci, Véronique Quellec, Timothy Wai, Ahmed Hamaï and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  8. Mitochondrial metabolism and cancer therapeutic innovation.Signal transduction and targeted therapy · 2025
    Review
  9. Article
  10. Imaging insights of FDG-PET from neonates to infants.Japanese journal of radiology · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Food for thought: Nutrient metabolism controlling early T cell development.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Rima ElhageInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Mairead KellyInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Nicolas Goudin *Platform for Image Analysis Center, SFR Necker, INSERM US 24 - CNRS UMS 3633, Paris, France.
Jérôme Megret *Platform for Cytometry, SFR Necker, INSERM US 24 - CNRS UMS 3633, Paris, France.
Agnès LegrandInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Ivan NemazanyyPlatform for Metabolic Analyses, SFR Necker, INSERM US 24 - CNRS UMS 3633, Paris, France.
Cécilia PatitucciMitochondrial Biology Group, Institut Pasteur, CNRS UMR 3691, Paris, France.
Véronique QuellecInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Timothy WaiMitochondrial Biology Group, Institut Pasteur, CNRS UMR 3691, Paris, France.
Ahmed HamaïInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Sophie EzineInstitut Necker Enfant-Malades (INEM), INSERM U1151-CNRS UMR 8253, Université de Paris, Paris, France.
Centre National de la Recherche Scientifique · FRInstitut Necker Enfants Malades · FRInserm · FRStructure fédérative de recherche NeckerInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies demonstrated that mitochondrial dynamics and metabolic pathways control T cell fate in the periphery. However, little is known about their implication in thymocyte development. Our results showed that thymic progenitors (CD3

Indexed as

Mitochondrial DynamicsThymus GlandCell DifferentiationCell Divisionglycolysismetabolomemitochondrial dynamicsOxPhosT cell progenitorsthymusβ-selection checkpoint

Identifiers

PMID38288115
PMCPMC10822881
OpenAlexW4390884245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.