Evidence map›Paper›PMID 38288083›Full record

ReviewERJ open research2024

Phenotypes and treatment outcomes in idiopathic pulmonary arterial hypertension patients with comorbidities.

Dirk Skowasch, Hans Klose, Ralf Ewert, Heinrike Wilkens, Manuel Richter, Stephan Rosenkranz, Gesine Setzer, Ekkehard Grünig, Michael Halank

Open access · goldAbstract readReview
In one paragraph

Review in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Dirk SkowaschHeart Center Bonn, Department of Medicine II, University Hospital Bonn, Bonn, Germany.
Hans KloseII. Medical Clinic and Polyclinic, Department of Pulmonology, Center for Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ralf EwertDepartment of Internal Medicine B, Internal Medicine, Pulmonology, Internal Intensive Care Medicine, University Medical Center Greifswald, Greifswald, Germany.
Heinrike WilkensInternal Medicine V - Pneumology, Saarland University Hospital and Faculty of Medicine Saarland University, Homburg, Germany.
Manuel RichterDepartment of Medicine II, Pulmonology, University Hospital Giessen, Giessen, Germany.
Stephan RosenkranzDepartment III of Internal Medicine - Cardiology, Pulmonology, Angiology and Internal Intensive Care Medicine, University Hospital Cologne, Cologne, Germany.
Gesine SetzerScientific and Medical Affairs, Janssen-Cilag GmbH, Neuss, Germany.
Ekkehard GrünigCenter for Pulmonary Hypertension, Thoraxklinik-Heidelberg gGmbH, and German Center for Lung Research (DZL), Heidelberg, Germany.
Michael HalankDivision of Pneumology, Medical Department - I, University Hospital Carl Gustav Carus of TU Dresden, Dresden, Germany.
German Center for Lung Research · DEJanssen (Germany) · DESaarland University · DEUniversität Hamburg · DEUniversity Hospital Bonn · DEUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Cologne · DEUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary arterial hypertension (IPAH) is often diagnosed in elderly patients with many comorbidities. Whereas a clear treatment strategy and risk assessment is recommended for patients with rare classical IPAH, monotherapy with phosphodiesterase type 5 inhibitors or endothelin receptor antagonists followed by regular follow-up and individualised therapy should be used for patients with many cardiopulmonary comorbidities. Here, we focus on these patients with IPAH and comorbidities, present a review of the literature with a focus on recently published work and summarise factors that may help to provide guidance for individualised treatment approaches in such patients.

Identifiers

PMID38288083
PMCPMC10823369
OpenAlexW4390061872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.