ArticleFrontiers in nutrition2023
Long-term iron supplementation combined with vitamin B6 enhances maximal oxygen uptake and promotes skeletal muscle-specific mitochondrial biogenesis in rats.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- The Effect of Whey Peptides and Micronutrients on Improving Exercise Performance in Mice.Nutrients · 2026Article
- Physiological and Metabolic Responses of Mongolian Horses to a 20 km Endurance Exercise and Screening for New Oxidative-Imbalance Biomarkers.Animals : an open access journal from MDPI · 2025Article
- The effects of different exercise training protocols on mitochondrial dynamics in skeletal and cardiac muscles of Wistar rats.Journal of orthopaedic surgery and research · 2025Article
- Iron Metabolism in the Recovery Phase of Critical Illness with a Focus on Sepsis.International journal of molecular sciences · 2024Review
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Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
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Abstract
Introduction: Iron is an essential micronutrient that plays a crucial role in various biological processes. Previous studies have shown that iron supplementation is related to exercise performance and endurance capacity improvements. However, the underlying mechanisms responsible for these effects are not well understood. Recent studies have suggested the beneficial impact of iron supplementation on mitochondrial function and its ability to rescue mitochondrial function under adverse stress Methods: In this study, we orally administered an iron-based supplement to rats for 30 consecutive days at a dosage of 0.66 mg iron/kg body weight and vitamin B6 at a dosage of 0.46 mg/kg. Results: Our findings reveal that long-term iron supplementation, in combination with vitamin B6, led to less body weight gained and increased VO Discussion: In conclusion, our study demonstrates that long-term iron supplementation, in combination with vitamin B6, increases VO
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