ArticleActa orthopaedica2024
Evaluation of simultaneous bilateral femoral distraction osteogenesis with antegrade intramedullary lengthening nails in achondroplasia with rhizomelic short stature: a retrospective study of 15 patients with a minimum follow-up of 2 years.
Article in Acta orthopaedica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 5 citations in OpenAlex.
- Premature Consolidation of Regenerated Bone During Limb Lengthening with External Fixation in Achondroplastic Patients: Case Series and Literature Review.Journal of clinical medicine · 2026Article
- Magnetic Intramedullary Lengthening Nails for Complex Lower Extremity Reconstruction: Functional Outcomes, Bone Healing, and Complications.Journal of clinical medicine · 2026Article
- Clinical and radiological outcomes of magnetically controlled intramedullary lengthening nails in adolescents and young adults: a retrospective cohort study.Journal of orthopaedic surgery and research · 2025Article
- What's new in pediatric lower limb reconstruction?Journal of children's orthopaedics · 2024Article
- Advancing pediatric bone sarcoma care: navigating complications and innovating solutions in limb salvage and reconstruction-why, when, and how to treat limb length inequalities.Acta orthopaedica et traumatologica turcica · 2024Review
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeBilateral femoral distraction osteogenesis in patients with achondroplasia is insufficiently reported. We aimed to perform the first study that exclusively analyzed simultaneous bilateral femoral distraction osteogenesis with motorized intramedullary lengthening nails via an antegrade approach in patients with achondroplasia focused on reliability, accuracy, precision, and the evolving complications. PATIENTS AND
methodsIn this retrospective singlecenter study we analyzed patients with achondroplasia who underwent simultaneous bilateral femoral lengthening with antegrade intramedullary lengthening nails between October 2014 and April 2019. 15 patients (30 femoral segments) of median age 14 years (interquartile range [IQR] 12-15) were available for analysis. The median follow-up was 29 months (IQR 27-37) after nail implantation.
resultsThe median distraction length per segment was 49 mm (IQR 47-51) with a median distraction index of 1.0 mm/day (IQR 0.9-1.0), and a median consolidation index of 20 days/cm (IQR 17-23). Reliability of the lengthening nails was 97% and their calculated accuracy and precision were 96% and 95%, respectively. The most common complication was temporary restriction of knee range of motion during distraction in 10 of 30 of the lengthened segments. 1 patient was treated with 2 unplanned additional surgeries due to premature consolidation.
conclusionThe method is reliable and accurate with few complications.
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